Combined endophthalmitis and orbital cellulitis in patients with corona virus disease (COVID-19)

Abdelkader, Mohamed Farouk; Elshafei, Ahmed Mohamed Kamal; Nassar, Mahmoud; Elela, Mostafa Ahmed Abu; Abdallah, Raafat Mohyeldeen Abdelrahman

doi:10.1186/s12348-021-00258-y

Cited by 8 publications

(7 citation statements)

References 20 publications

(25 reference statements)

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“…Of these, only one patient had paranasal sinusitis suggesting a distant source of infection in the rest. The authors suggested generalized poor immunity of patients, direct viral infection, and multisystem inflammatory syndrome related to COVID-19 as possible mechanisms of this unusual ophthalmic manifestation 160 …”

Section: Orbital Manifestations Of Coronavirus Disease 2019mentioning

confidence: 99%

“…Orbital apex syndrome is characterized by the involvement of the optic nerve and cranial nerves 3, 4, and 6 and the first division of the trigeminal nerve with painful visual loss, ophthalmoplegia, ptosis, proptosis, and loss of sensations 159 . Abdelkader et al 160 reported 9 cases of simultaneous unilateral endophthalmitis with orbital cellulitis as a presenting feature of COVID-19 infection. Of these, only one patient had paranasal sinusitis suggesting a distant source of infection in the rest.…”

Section: Orbital Manifestations Of Coronavirus Disease 2019mentioning

confidence: 99%

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Update on coronavirus disease 2019: Ophthalmic Manifestations and Adverse Reactions to Vaccination

Lin,

Sen,

Gupta

et al. 2023

Asia-Pacific Journal of Ophthalmology

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The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 was one of the most devastating public health issues in recent decades. The ophthalmology community is as concerned about the COVID-19 pandemic as the global public health community is, as COVID-19 was recognized to affect multiple organs in the human body, including the eyes, early in the course of the outbreak. Ophthalmic manifestations of COVID-19 are highly variable and could range from mild ocular surface abnormalities to potentially sight and life-threatening orbital and neuro-ophthalmic diseases. Furthermore, ophthalmic manifestations may also be the presenting or the only findings in COVID-19 infections. Meanwhile, global vaccination campaigns to attain herd immunity in different populations are the major strategy to mitigate the pandemic. As novel vaccinations against COVID-19 emerged, so were reports on adverse ophthalmic reactions potentially related to such. As the world enters a post-pandemic state where COVID-19 continues to exist and evolve as an endemic globally, the ophthalmology community ought to be aware of and keep abreast of the latest knowledge of ophthalmic associations with COVID-19 and its vaccinations. This review is a summary of the latest literature on the ophthalmic manifestations of COVID-19 and the adverse ophthalmic reactions related to its vaccinations.

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Section: Orbital Manifestations Of Coronavirus Disease 2019mentioning

confidence: 99%

Section: Orbital Manifestations Of Coronavirus Disease 2019mentioning

confidence: 99%

Update on coronavirus disease 2019: Ophthalmic Manifestations and Adverse Reactions to Vaccination

Lin,

Sen,

Gupta

et al. 2023

Asia-Pacific Journal of Ophthalmology

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“…A few studies have also reported COVID-19-related orbital cellulitis and sinusitis [ 55 , 64 , 65 , 66 ]. It was shown that only 1 among 2742 patients in India presented orbital cellulitis secondary to pansinusitis [ 66 ].…”

Section: The Orbital Regionmentioning

confidence: 99%

How Does SARS-CoV-2 Affect Our Eyes—What Have We Learnt So Far about the Ophthalmic Manifestations of COVID-19?

Baj

Forma

Teresińska

et al. 2022

JCM

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The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection has become a worldwide threat resulting in a pandemic in 2020. SARS-CoV-2 infection manifests itself as coronavirus disease 2019 (COVID-19) that is evidenced in a vast number of either specific or nonspecific symptoms. Except for typical (but nonspecific) symptoms such as fever, dry cough, or muscle weakness, the infected patients might also present atypical symptoms including neurological, dermatological, or ophthalmic manifestations. This paper summarizes the current state of knowledge regarding the onset, progression, and types of ophthalmic symptoms induced by SARS-CoV-2 infection recognized amongst the infected patients.

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“…22 Agarwal et al, 23 them, with 2 being culture negative. 23 Abdelkader et al 24 reported on 9 patients with simultaneous orbital cellulitis and endophthalmitis. Vitreous cultures had been negative, and the visual outcome was poor in those who survived.…”

Section: Endophthalmitis and Covid-19mentioning

confidence: 99%

“…Vitreous cultures had been negative, and the visual outcome was poor in those who survived. 24 Bilgic et al, 25 Stenotrophomonas maltofila. 25 All the patients had improved following PPV with intravitreal antibiotics 25 .…”

Section: Endophthalmitis and Covid-19mentioning

confidence: 99%

Endophthalmitis and COVID-19: A Narrative Literature Review

Markov¹,

Hristova²,

Andonova³

et al. 2022

sjo

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Endophthalmitis is a severe form of intraocular inflammation which is caused by bacteria or fungi. It is a medical emergency with an imminent threat to vision and permanent structural and functional complications. The condition affects the anterior and posterior segments of the eye. It may be either exogenous – following penetrating trauma or intraocular surgery, or endogenous, in which the pathogens enter the eye hematogenous. The diagnosis is based on the clinical picture and on specialized testing – aqueous and/or vitreous cultures, with or without additional PCR for panbacterial and panfungal primers. If endogenous endophthalmitis is suspected, blood and urine cultures may also be performed. The most common bacterial pathogens in acute postoperative endophthalmitis belong to the Staphylococcus and Streptococcus groups. Endogenous endophthalmitis is most frequently fungal and caused by Candida. The incidence of post-traumatic endophthalmitis ranges from 0.9 to 17% and of postoperative - from 0.016 to 5.7%, depending on the surgical procedure and the geographic location. Endogenous endophthalmitis has been observed in up to 8% of all cases. Therapy is urgent and may include intravitreal medications or pars plana vitrectomy (PPV), according to the Endophthalmitis Vitrectomy Study criteria. The combination of COVID-19-associated severe pneumonia, systemic corticosteroid therapy, and diabetes appear to be risk factors for endogenous endophthalmitis. The ethology has mostly been linked to fungal infections, especially Candida, as in the pre-COVID-19 era. There has been a tendency to perform PPV with intravitreal medications as the primary procedure, but the results have been mixed.

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Combined endophthalmitis and orbital cellulitis in patients with corona virus disease (COVID-19)

Cited by 8 publications

References 20 publications

Update on coronavirus disease 2019: Ophthalmic Manifestations and Adverse Reactions to Vaccination

Update on coronavirus disease 2019: Ophthalmic Manifestations and Adverse Reactions to Vaccination

How Does SARS-CoV-2 Affect Our Eyes—What Have We Learnt So Far about the Ophthalmic Manifestations of COVID-19?

Endophthalmitis and COVID-19: A Narrative Literature Review

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