Combined Glaucoma and Cataract: An Overview

Jiménez-Román, Jesús; Prado-Larrea, Carolina; Laneri-Pusineri, Luis; González-Salinas, Roberto

doi:10.5772/intechopen.73584

Cited by 5 publications

(4 citation statements)

References 79 publications

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“…Cataract and glaucoma are common diseases with a steeply increasing incidence over the age of 60 years [ 1 ]; both conditions occur more frequently with advancing age. Cataract and glaucoma frequently coexist in our patient population [ 2 ]. They are serious conditions and can cause visual loss.…”

Section: Introductionmentioning

confidence: 99%

Assessment of the Levels of Knowledge Regarding Cataract and Glaucoma in Saudi Arabia and Measurement of the Ability to Differentiate Between the Two

Alammar¹,

Alabdulkareem²,

Abu-amara³

et al. 2021

Cureus

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Section: Introductionmentioning

confidence: 99%

Assessment of the Levels of Knowledge Regarding Cataract and Glaucoma in Saudi Arabia and Measurement of the Ability to Differentiate Between the Two

Alammar¹,

Alabdulkareem²,

Abu-amara³

et al. 2021

Cureus

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“…Cataract surgery alone is considered to result in long-term IOP reduction. The mechanism behind IOP reduction through cataract surgery is still controversial [ 13 , 14 , 15 ]. Compression of Schlemm’s canal is assumed to follow an increase in lens volume with age, providing traction over the zonules and subsequently on the ciliary body.…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, a short-term increase in pressure during cataract surgery may lead to increased patency in the trabecular meshwork and Schlemm’s canal. Despite the existence of all these theories, disagreement still exists on the potency, clinical importance, and long-term variability of each process [ 13 , 14 , 15 ].…”

Section: Discussionmentioning

confidence: 99%

Position of the ISTENT Inject® Trabecular Micro-Bypass System Visualized with the NIDEK GS-1 Gonioscope—A Postoperative Analysis

Zimmermann¹,

Storp²,

Merté³

et al. 2023

JCM

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Glaucoma is one of the leading causes of irreversible blindness globally and is characterized by the gradual loss of retinal ganglion cells. The primary risk factor for the development and progression of glaucoma is increased intraocular pressure (IOP). Numerous surgical interventions exist to lower IOP should conservative therapy fail. One trend in recent years has been minimally invasive glaucoma surgery (MIGS) as an alternative to traditional methods. The ISTENT inject® is an ab interno trabecular micro-bypass implant designed to be implanted through the trabecular meshwork into the Schlemm’s canal to lower IOP. The aim of the study was the postoperative visualization and description of the positioning of the ISTENT inject® using automated circumferential goniophotography. Patients with symptomatic cataracts and mild to moderate primary open-angle glaucoma (POAG), pseudoexfoliation glaucoma (PEX), and pigment-dispersion glaucoma were included who underwent combined cataract surgery with the ISTENT inject® and received postoperative automated gonioscopy with the NIDEK Gonioscope GS-1 to visualize the location of the implant. Twenty-four implants of 14 eyes in 11 patients could be visualized. Out of the implants, 14.3% were in the trabecular meshwork, 46.4% were at the border between the trabecular meshwork and scleral spur, 25% were below the trabecular meshwork, and 14.3% of the implants were not detectable in the gonioscopy. In the overall cohort, a statistically significant IOP reduction was found over the 12-month postoperative observation period. Even in three eyes, in each of which both stents were located below the trabecular meshwork, an IOP reduction over 12 months was observed compared to the baseline IOP. In this study, vertical two-dimensional positioning of the ISTENT inject® was performed for the first time using NIDKE GS-1 automated 360° goniophotography. The method is suitable for postoperative visualization, control, and documentation of positioning after ISTENT inject® implantation. Further studies are needed to analyze the correlation between positioning of the ISTENT inject® in the chamber angle and postoperative IOP reduction.

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“…Cataracts and glaucoma are the top two leading causes of blindness in individuals above 50 years, with a global prevalence of 15.2 and 3.6 million cases, respectively, in 2020 [1]. As the prevalence of these two diseases increases with age, it is not uncommon to find them coexisting together in a single individual [2][3][4][5]. Some studies have even suggested that glaucoma is a risk factor for cataract development and progression [6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Remarkable Improvements After Cataract Surgery in a Presumed “End-Stage” Glaucoma Patient: A Case Report

El Helwe,

Ingram,

Liebman

et al. 2023

Cureus

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Predicting the visual outcome after cataract extraction can be challenging in glaucoma patients who develop cataracts. Here, we demonstrate the case of a patient with advanced glaucoma and a mild-to-moderate cataract at initial presentation, who demonstrated remarkable improvement in visual acuity following a period of controlled intraocular pressure (IOP) and the removal of a matured cataract at the time of surgery. A 64-year-old Haitian woman with severe mixed-mechanism glaucoma and hand motion vision in both eyes (OU) presented with intraocular pressures of 38 mmHg OD (oculus dexter/right eye) and 41 mmHg OS (oculus sinister/left eye) while on three IOP-lowering agents. Her medications were escalated to six IOP-lowering medications, and she underwent bilateral transscleral laser cyclophotocoagulation with both micropulse and continuous wave probes simultaneously. Postoperatively, IOPs dropped to 7 and 9 mmHg in the right and left eyes, respectively, and remained at or below target on three topical agents for the remainder of her follow-up. Contrastingly, the patient's cataract had progressed, and the decision was made to undergo cataract extraction OU sequentially. The subsequent clinical course demonstrated progressive visual improvement with 20/80 best-corrected visual acuity OU and increased independence with activities of daily living. This case illustrates the potential for visual improvement in an advanced glaucoma patient after removing a matured cataract despite limited prior expectations. Ocular comorbidities complicate but do not necessarily preclude appropriate interventions that may improve patients' vision-related quality of life.

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Combined Glaucoma and Cataract: An Overview

Cited by 5 publications

References 79 publications

Assessment of the Levels of Knowledge Regarding Cataract and Glaucoma in Saudi Arabia and Measurement of the Ability to Differentiate Between the Two

Assessment of the Levels of Knowledge Regarding Cataract and Glaucoma in Saudi Arabia and Measurement of the Ability to Differentiate Between the Two

Position of the ISTENT Inject® Trabecular Micro-Bypass System Visualized with the NIDEK GS-1 Gonioscope—A Postoperative Analysis

Remarkable Improvements After Cataract Surgery in a Presumed “End-Stage” Glaucoma Patient: A Case Report

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