Combined hMG/hCG Treatment in Subfertile Men With Idiopathic Normogonadotrophic Oligozoospermia

Schill, Wolf‐Bernhard; Jüngst, Dieter; Unterburger, P.; Braun, Siegmund

doi:10.1016/s0022-5347(17)51048-4

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2012

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“…Schill et al. [9] reported a 15.3 million/mL increase in mean sperm concentration after 3 months of treatment with hCG and hMG in men with idiopathic oligospermia and normal levels of gonadotropins. Physicians have used clomiphene citrate, hCG and hMG as treatment for idiopathic oligospermia, and numerous studies have reported improvement in semen quality and increased pregnancy rates among the partners of men in whom these agents were administered [9,10].…”

Section: Discussionmentioning

confidence: 99%

Optimization of spermatogenesis‐regulating hormones in patients with non‐obstructive azoospermia and its impact on sperm retrieval: a multicentre study

et al. 2012

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What ' s known on the subject? and What does the study add? Clomiphene citrate, hCG and human menopausal gonadotropin (hMG) are widely used in treatment of oligospermia, because they increase FSH and testosterone which are essential for spermatogenesis. Finding a sperm in non-obstructive azoospermia for intracytoplasmic sperm injection is a challenge and much effort is required to reach the optimum method of sperm retrieval.

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Section: Discussionmentioning

confidence: 99%