Combined low dose local anesthetics and opioids versus single use of LA for transurethral urological surgery: A meta-analysis

Ding, Yan; Li, M; Chen, L; Zhang, Q; Jiang, Aihua; Chi, Yuan

doi:10.4103/1119-3077.151055

Niger J Clin Pract

2015

DOI: 10.4103/1119-3077.151055

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Combined low dose local anesthetics and opioids versus single use of LA for transurethral urological surgery: A meta-analysis

Yan Ding¹,

M Li²,

L Chen³

et al.

Abstract: Combined low dose LA and opioids is a better choice for patients received transurethral surgery compared with single use of intrathecal LA.

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2016

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References 27 publications

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Intrathecal Sufentanil Does Not Reduce Shivering During Neuraxial Anesthesia: A Meta-Analysis

et al. 2016

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BackgroundWe performed this meta-analysis to evaluate the efficacy of intrathecal sufentanil in preventing shivering during neuraxial anesthesia.Material/MethodsWe searched the Cochrane Library, PubMed, and Embase for all randomized controlled trials (RCT) on use of intrathecal sufentanil for preventing shivering during neuraxial anesthesia. References of retrieved articles were also screened. The quality of the studies was evaluated by the method recommended by the Cochrane Collaboration. Meta-analysis was conducted using the Cochrane Collaboration’s RevMan 5.3 software. The primary outcome was incidence and severity of shivering, and the secondary outcomes were drug-related complications of pruritus, nausea, vomiting, hypotension, and bradycardia.ResultsEight original RCTs investigating a total of 1032 patients, of whom 599 received sufentanil and 473 received placebo, met the inclusion criteria. Compared to the placebo group, sufentanil did not reduce incidence of shivering (OR, 0.60; 95% CI, 0.35 to 1.01; P=0.06), but it increased the incidence of pruritus (OR, 12.52; 95% CI, 5.07 to 30.91; P<0.00001). Compared to the placebo group, sufentanil did not increase the incidence of nausea (OR, 0.69; 95% CI, 0.41 to 1.16; P=0.16), hypotension (OR, 0.93; 95% CI, 0.62 to 1.41; P=0.74), or bradycardia (OR, 0.86; 95% CI, 0.41 to 1.82; P=0.70). In addition, sufentanil reduced the incidence of vomiting during neuraxial anesthesia (OR, 0.45; 95% CI, 0.22 to 0.92; P=0.03).ConclusionsNeither epidural nor subarachnoid intrathecal sufentanil reduced shivering during neuraxial anesthesia, but it did increase the incidence of pruritus.

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Intrathecal Sufentanil Does Not Reduce Shivering During Neuraxial Anesthesia: A Meta-Analysis

et al. 2016

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Combined low dose local anesthetics and opioids versus single use of LA for transurethral urological surgery: A meta-analysis

Abstract: Combined low dose LA and opioids is a better choice for patients received transurethral surgery compared with single use of intrathecal LA.

Cited by 1 publication

References 27 publications

Intrathecal Sufentanil Does Not Reduce Shivering During Neuraxial Anesthesia: A Meta-Analysis

Intrathecal Sufentanil Does Not Reduce Shivering During Neuraxial Anesthesia: A Meta-Analysis

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