2013
DOI: 10.1016/j.clinbiochem.2013.06.011
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Combined measurement of N-terminal pro-B-type natriuretic peptide and highly sensitive cardiac troponin T for diagnosis and monitoring of heart injury in chronic Chagas' disease

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Cited by 10 publications
(5 citation statements)
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“…Combining multiple factors for risk stratification appears to be a promising approach. The measurement of natriuretic peptides in combination with biomarkers indicating myocardial necrosis (TnT) and inflammation (high-sensitivity C-reactive protein; hs-CRP) has been shown to improve risk prediction [ 13 , 19 , 20 ]. Additionally, the presence of ventricular dysfunction, particularly when the ejection fraction is less than 25.5%, has been associated with lower survival and was confirmed in this study [ 21 ].…”
Section: Discussionmentioning
confidence: 99%
“…Combining multiple factors for risk stratification appears to be a promising approach. The measurement of natriuretic peptides in combination with biomarkers indicating myocardial necrosis (TnT) and inflammation (high-sensitivity C-reactive protein; hs-CRP) has been shown to improve risk prediction [ 13 , 19 , 20 ]. Additionally, the presence of ventricular dysfunction, particularly when the ejection fraction is less than 25.5%, has been associated with lower survival and was confirmed in this study [ 21 ].…”
Section: Discussionmentioning
confidence: 99%
“…A study assessing it in combination with NT-proBNP that included samples from 137 T. cruzi-infected patients with several forms of the disease found that levels of both markers were increased in those individuals with cardiomyopathy in comparison to the asymptomatic ones (28). Moreover, their values were increased accordingly to the severity of the cardiomyopathy (28).…”
Section: Biochemical Markers Of Disease Progressionmentioning
confidence: 99%
“…A study assessing it in combination with NT-proBNP that included samples from 137 T. cruzi-infected patients with several forms of the disease found that levels of both markers were increased in those individuals with cardiomyopathy in comparison to the asymptomatic ones (28). Moreover, their values were increased accordingly to the severity of the cardiomyopathy (28). Plasma leptin levels and their relation to different forms of the disease were also studied in combination with NT-proBNP in 52 T. cruzi-infected patients, and those patients with heart failure had higher levels of NT-ProBNP and lower levels of leptin than controls (29).…”
Section: Biochemical Markers Of Disease Progressionmentioning
confidence: 99%
“…A relatively under-explored option for risk prediction in CD cardiomyopathy that may prove very useful in this context are serum biomarkers [7]. Nevertheless, few studies have addressed their role in CCM, which warrants direct confirmation given its unique pathogenesis [8][9][10][11].…”
Section: Introductionmentioning
confidence: 99%