Combined mediastinal and retroperitoneal fibrosis

Combined retroperitoneal and mediastinal fibrosis associated with variceal haemorrhage

“…Methysergide has been associated with retroperitoneal fibrosis but was not taken by either subject prior to the onset of symptoms. Case 2 subsequently used the related hallucinogen lysergic acid diethylamide 4 . Adhesions in the peritoneum and pericardial sac in addition to those in the mediastinum and retroperitoneum in Case 2 suggest a generalised fibrosing tendency, although keloid formation was not present.…”