Increasing environmental and economic pressures have led to numerous innovations in the logistics sector, including integrated people and freight transport (IPFT). Despite growing attention from practitioners and researchers, IPFT lacks extensive research coverage. This study aims to bridge this gap by presenting a general framework and making several key contributions. It identifies, researches, and explains relevant terminologies, such as cargo hitching, freight on transit (FoT), urban co-modality, crowd-shipping (CS), occasional drivers (OD), crowdsourced delivery among friends, and share-a-ride, illustrating the interaction of IPFT with different systems like the sharing economy and co-modality. Furthermore, it classifies IPFT-related studies at strategic, tactical, and operational decision levels, detailing those that address uncertainty. The study also analyzes the opportunities and challenges associated with IPFT, highlighting social, economic, and environmental benefits and examining challenges from a PESTEL (political, economic, social, technological, environmental, and legal) perspective. Additionally, it discusses practical applications of IPFT and offers recommendations for future research and development, aiming to guide practitioners and researchers in addressing existing challenges and leveraging opportunities. This comprehensive framework aims to significantly advance the understanding and implementation of IPFT in the logistics sector.