Combined Scintiscans in the Diagnosis of Thyroid Carcinomas

Makimoto, Kazuo; Ohmura, Masaki; Tamada, Akira; Kanoh, Naoyuki; Murakami, Takashi; Iida, Yasuhiro; Kasagi, Kanji; Endo, Keigo; Konishi, Junji; Torizuka, K

doi:10.1080/00016489.1985.12005672

Cited by 8 publications

(3 citation statements)

References 5 publications

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“…T1-20 1 can be used for wholebody imaging in patients with thyroid carcinoma. The advantage of T1-20 1 is that tumors are indistinguishable from adenomas and thyroiditis [9,10]. Ochi et a1 [ l l ] found that most malignant tumors retained T1-201 while benign lesions cleared the tracer faster.…”

Section: Less Used Radiotracersmentioning

confidence: 98%

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Modern methodologies of differentiating thyroid masses

Mafee

Capek

Blend

et al. 1991

Seminars in Surgical Oncology

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The rational treatment of thyroid diseases requires an understanding of the thyroid function and an accurate evaluation of its functional (endocrine), as well as it morphological alteration. There are several different imaging techniques which are available and are in use in the evaluation of thyroid diseases. In this article we present a protocol for the use of diagnostic imaging to evaluate a focal thyroid mass, a diffusely enlarged gland, regional, and distant metastatic disease. The current diagnostic applications of radionuclide scanning, ultrasound, computed tomography, and magnetic resonance imaging (MRI) will be discussed.

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Section: Less Used Radiotracersmentioning

confidence: 98%

“…CT and MRI serve three primary purposes: 1) The exact location and degree of invasiveness of large and/or invasive thyroid cancers can be evaluated [4-71 (Figs. 6- 10). Substernal or retrotracheal extension of large thyroid tumors or goiters can be assessed (Fig.…”

Section: Ct and Mrimentioning

confidence: 99%

Modern methodologies of differentiating thyroid masses

Mafee

Capek

Blend

et al. 1991

Seminars in Surgical Oncology

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“…In the diagnosis of nodular goiter, many authors have reported the accumulation of this radionuclide in thyroid cancers and their lymphnode metastasis. [1][2][3][4][5][6][7] Meanwhile, since a significant fraction of adenomas or other benign conditions also appear positive in the scintigram, a single radiothallium image could not be a satisfactory test to use in estimating the Received February 4, 1991, revision accepted April 3, 1991. For reprints contact: Takashi Misaki, Department of Radiology, Kyoto City Hospital, Mibuhigashitakada, Nakagyoku, Kyoto 604, JAPAN. histological nature of a given struma nodosa.…”

Section: Introductionmentioning

confidence: 99%

Limited value of delayed radiothallium image in the diagnosis of nodular goiter

et al. 1991

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To test whether delayed thallium image can improve the diagnostic accuracy of thyroid tumor, we have reviewed 35 patients with cold nodules of proven histopathology. Early and delayed images were taken 10-20 min and 3-4 hr postinjection, respectively. In this study, a thyroid nodule was interpreted as malignant if it had normal or increased uptake on early scan and more residual radioactivity than paranodular tissue on delayed scan. In the eighteen patients who had carcinoma, a disappointing 44% false negative rate was observed. No significant difference was seen between retention-positive and negative cases in tumor size or histological type of cancer. Nor could any demographic bias explain the low sensitivity. Of the six false negatives, macroscopic cystic degeneration was seen in two cases, but tumors in the other four were grossly solid. Considering the histological heterogeneity often seen within a thyroid tumor, the portion with increased retention of radiothallium may be too small to be detected in the false negative cases. Furthermore, 3 false positive readings were obtained in 17 patients with benign conditions. We conclude that the contribution of the delayed thallium image was quite limited in predicting or ruling out malignancy in nodular goiters.

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Avid thallium-201 uptake in hepatic carcinoid metastases

Nour

et al. 1993

Eur J Nucl Med

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While radiolabelled somatostatin analogues sensitively detect extrahepatic carcinoid tumour, intrahepatic metastases are frequently not visualised due to somatostatin accumulation in normal hepatic tissues. We report a case of avid thallium-201 uptake in multiple hepatic carcinoid metastases using single-photon emission tomography (SPET) and compare this to a SPET technetium-99m sulphur colloid scan in the same patient. The 99mTc sulphur colloid images demonstrate multiple focal defects at the site of known metastases in the hepatic right lobe (confirmed on both CT and surgery). However, there is avid uptake of thallium in the metastases on comparative SPET slices. 201Tl may be a useful agent for the detection and localisation of carcinoid tumour and in particular of intrahepatic carcinoid metastases.

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Combined Scintiscans in the Diagnosis of Thyroid Carcinomas

Cited by 8 publications

References 5 publications

Modern methodologies of differentiating thyroid masses

Modern methodologies of differentiating thyroid masses

Limited value of delayed radiothallium image in the diagnosis of nodular goiter

Avid thallium-201 uptake in hepatic carcinoid metastases

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