“…Elective TAVR combined with TEVAR has been reported in a few patients with successful outcome. 21–25 TAVR has also been used electively to treat pure severe native aortic valve regurgitation, albeit in a much smaller number of patients compared to those with aortic stenosis. 26,27 However, absence of aortic valve calcification, which is common with pure native aortic valve regurgitation, may compromise fixation of the implanted valve frame to the aortic annulus, leading to malpositioning and need for implantation of a second valve.…”