Combined Surgical-Orthodontic Treatment of Patients With Severe Parry-Romberg Syndrome

Abstract

: Parry-Romberg syndrome (PRS) refers to a relatively rare dysfunction disease that is characterized by chronic progressive maxillofacial atrophy, especially one side of facial skin, subcutaneous tissue, muscle, and bone. According to the atrophy degree of skin, subcutaneous tissue, and skeleton in the area innervated by the trigeminal nerve, PRS can be classified into mild, moderate, and severe. In general, cases with different severity have specific treatment regimens. For mild and moderate cases, soft tissue augmentation techniques are the optimal strategy for aesthetic reconstruction. In this study, the authors report a 19-year-old female with severe PRS. Considering the severity of the case, a combined surgical and orthodontic treatment was performed, which was involved in alveolar bone augmentation, preoperative and postoperative orthodontic treatment in combination with orthognathic surgery, medpor filling of zygomatic and maxillary complex, free fat grafting, as well as angulus oris and lip trimming. Comprehensive treatment is recommended for severe cases with extensive atrophy of soft tissue and craniofacial bone, obvious deviation of the chin and occlusal plane.

Parry Romberg Sendromlu Pedi̇atri̇k Bi̇r Hastanin Nadi̇r Oral Bulgulari: Bi̇r Olgu Sunumu

“…Travma, enfeksiyon, genetik faktör, epilepsi, migren, trigeminal nevrit, lenfositik nörovaskülit, lokalize skleroderma, endokrin bozukluğu, otoimmünite, sempatik sinir sisteminin hiper-veya hipo-aktivitesi ve serebellumun yağ metabolizmasında bozukluk gibi çok sayıda neden ileri sürülmüştür. 11,12 Az sayıda hastada vitiligo, tiroid sorunları, sistemik skleroz, inflamatuar barsak hastalığı, romatoid artrit, ankilozan spondilit, sistemik lupus eritematozus ve multipl skleroz gibi diğer otoimmün bozukluklar da rapor edilmiştir. Eşlik eden ağız ve çevre dokularında alın, yanaklar, çene, dudaklar, dişler, diş etleri ve dil tutulumu görülmüştür.…”