Combined transcriptomic and metabolic analyses reveal potential mechanism for fruit development and quality control of Chinese raspberry (Rubus chingii Hu)

Integrative analysis of the metabolome and transcriptome reveals the potential mechanism of fruit flavor formation in wild hawthorn (Crataegus chungtienensis)

“…The content of flavonoids in cultivated hawthorns ( C. pinnatifida var. major ), lemon, raspberry and blackberry fruits also showed the same accumulation pattern ( Chen et al, 2021 ; Wu et al, 2022 ; Zhang et al., 2022a , Zhang et al., 2022b ; Zhu et al, 2018 ). Studies have found that flavonoids have a bitter taste which can protect plants from animal damage by changing the palatability of plants, reducing the nutritional value of fruits, and even may become toxins ( Drewnowski, 2001 ; Harborne and Williams, 2000 ; Mierziak et al, 2014 ).…”

“…Combinatorial analysis of transcriptome and metabolome is widely used in the study of fruit flavor, which provides important clues for improving fruit flavor and quality ( Chen et al, 2021 ; Peng et al, 2022 ; Wang et al, 2022 ). The taste of fruits is composed of flavor, and sweetness and sourness are important factors that affect the taste of fruit.…”

Combined transcriptome and metabolome analysis of strawberry fruits in response to powdery mildew infection

“…Multivariate statistical analysis methods used principal component analysis and the partial least squares method‐discriminant analysis (Barker & Rayens, 2003). Differential accumulative metabolites are defined as those that exhibit multiples of ≥1.2 or ≤0.83, variable importance ≥ 1, and p < .05 (Z. Chen, Jiang, et al., 2021). Cluster analysis of differential metabolites was conducted with log 2 transformation and zero‐mean normalization of data.…”

“…Differential accumulative metabolites are defined as those that exhibit multiples of ≥1.2 or ≤0.83, variable importance ≥ 1, and p < .05 (Z. Chen, Jiang, et al, 2021). Cluster analysis of differential metabolites was conducted with log 2 transformation and zero-mean normalization of data.…”

Bioactive components, pharmacological effects, and drug development of traditional herbal medicine Rubus chingii Hu (Fu-Pen-Zi)

“…β-sitosterol is a compound of steroid with a hydroxyl and a double bond at positions C-3 and C-5, and 10-carbon alkyls on the side chain of C-17 ( 13 ). The structure of plant sterols such as carotene and β-sitosterol is similar to that of cholesterol, which can effectively reduce the concentration of cholesterol and low-density lipoprotein in the blood ( 22 ). Desai et al ( 23 ) studied the specific mechanism of the lipid-lowering effect of β-sitosterol.…”