2023
DOI: 10.3889/oamjms.2023.7551
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Combined Treatment Effect of Topical CM-hWJMSCs and Oral Moringa oleifera extract on Wound Healing of Diabetic Rat

Abstract: AIMS: The aim of the study was to determine the activity of topical conditioned medium (CM) mesenchymal stem cells as single or combined with oral therapy of Moringa oleifera extract (ME) in lowering blood glucose levels and healing diabetic wounds. MATERIALS AND METHODS: Male Sprague-Dawley rats were induced hyperglycemia with Streptozotocin and injured by a biopsy punch on the dorsal side. Then, the rats were divided into five groups, namely, the CM group, which was given topically; the CM–ME group, which wa… Show more

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“…The examination was carried out under a microscope covered with glass. The parameters measured were the area of inflammation, angiogenesis, and collagen tissue area using a polarized light microscope (Leica, Wetzlar, Germany) ( Laksmitawati et al, 2023 ; Suvik & Effendy, 2012 ).…”
Section: Methodsmentioning
confidence: 99%
“…The examination was carried out under a microscope covered with glass. The parameters measured were the area of inflammation, angiogenesis, and collagen tissue area using a polarized light microscope (Leica, Wetzlar, Germany) ( Laksmitawati et al, 2023 ; Suvik & Effendy, 2012 ).…”
Section: Methodsmentioning
confidence: 99%