Combined Treatment of Therapeutic Laser and Herbal Application Improves the Strength of Repairing Ligament

Fung, Dicky T.C.; Ng, Gabriel Y.F.; Leung, Mason C.P.

doi:10.1080/03008200591008473

Cited by 6 publications

(6 citation statements)

References 43 publications

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“…Preliminary findings of this study indicated that using combined MAT plus LAT exerted a relatively better effect than using MAT or LAT alone. This result agrees with the synergistic effect of combined therapeutic laser and herbal medication protocols on injured medial collateral ligaments (MCLs) of rat knees [ 24 ]. The combined protocols further enhanced the biomechanical properties of repairing rat MCLs in comparison with separate applications [ 24 ].…”

Section: Discussionsupporting

confidence: 85%

Using auriculotherapy for osteoarthritic knee among elders: a double-blinded randomised feasibility study

Suen

Yeh

Yeung

2016

BMC Complement Altern Med

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BackgroundOsteoarthritic knee (OA knee) is a common condition in the elderly. Exploration of non-invasive complementary therapies for OA knee is warranted given the limitations of pharmacologic therapies. Auriculotherapy (AT) is a therapeutic method in which specific points on the auricle are stimulated to treat various disorders of the body, and the therapeutic value and synergistic effect of laser auriculotherapy (LAT) when combined with magneto-auriculotherapy (MAT) merits further investigation.MethodsThis study adopted a double-blinded four-arm randomized placebo design. The aims of study are (1) to assess the feasibility of AT among elders with OA knee in a future large-scale study, including the use of blinding in subjects and evaluators, acceptance of treatment protocol, and estimating the effect size and attrition rate; and (2) to evaluate the preliminary effect of AT in elders with OA knee. Subjects were randomly divided into four groups with different modes of AT with/without placebo objects. A total of 43 subjects completed the 6-week intervention and post-assessment. Assessments included a numerical rating scale of pain (NRS), the timed-up-and-go test (TUGT), and standard goniometer measurements during knee flexion and extension, Kruskal–Wallis test was used to evaluate differences among groups, and Wilcoxon sign-ranked test for examining within-group comparison.ResultsPreliminary results indicated the absence of differences in the NRS, TUGT, and active/passive knee flexion and extension at baseline, as well as post-therapy, between the four groups. Even though the differences of these parameters between groups were not significant, the relative differences of NRS and TUGT in subjects who received combined MAT plus LAT were higher than those treated with MAT or LAT alone, or the placebo group. Four of the six parameters demonstrated significant within group differences in subjects who received MAT and/or LAT, whereas no significant differences were found in the placebo group.ConclusionThis study demonstrates that the AT protocol adopted in this study for elders with OA knee is feasible and could be applied in future larger-scale study. Larger sample size should be considered in a future trial to determine the causal relationship between treatment and effect.Trial RegistrationClinicalTrials.gov: NCT02352636. Registered on 23 January 2015.

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Section: Discussionsupporting

confidence: 85%

Using auriculotherapy for osteoarthritic knee among elders: a double-blinded randomised feasibility study

Suen

Yeh

Yeung

2016

BMC Complement Altern Med

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“…LLLT is a widely studied treatment option for several different types of acute and chronic medical problems, and has been studied mostly in different types of animals until now. Some of the studies using animals as the target subjects have found some correlation between the use of LLLT and decreased healing times of wounds when compared to the control groups 6,7 . As more evidence of the statistically proven benefits of LLLT in animal trials have surfaced, some researchers have begun to shift their view to whether this treatment may have any beneficial properties in human wound healing.…”

Section: Resultsmentioning

confidence: 99%

To evaluate the safety and efficiency of low level laser therapy (LLLT) in treating decubitus ulcers: a review

Ahmed¹

2015

SPIE Proceedings

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Introduction: Pressure sores (decubitus ulcer) are a serious problem in health care management, especially for middleaged to older people who are bed-ridden. Although preventative measures are used, the condition remains common and development of novel, improved treatment methods are desirable. This article reviews the application of laser-based methods, previously shown to be effective in accelerating wound-healing in animal models and in the treatment of decubitus ulcers in humans. Methods: About 23 scientific articles on the effect of low level laser therapy (LLLT) on wound healing in animals and humans from 2000-2014 were reviewed. Additionally, results of several randomized controlled trials (RCTs) were reviewed, and compared with other treatment methods available. Results: Whilst carefully controlled, laboratory-based animal studies indicated that LLLT can reduce healing time for several types of injuries, however similar studies in humans failed to demonstrate consistent beneficial effects in the clinical setting. An acceleration of decubitus ulcer healing has been occasionally found, although limited to certain wavelengths and sometimes only in combination with other types of therapies. Indeed, some of the clinical articles indicated that certain laser wavelengths can have detrimental effects on time of healing. Conclusions: To date, there remains no convincing evidence that LLLT has consistent medical benefit in treating decubitus ulcers. Caution should be applied when considering LLLT since only certain wavelengths utilized have shown beneficial effects. It is concluded that, more RCTs are needed since, there is no clinical justification for LLLT, alone or in combination with other methods, in treating decubitus ulcers.

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“…15,16 There have been a few studies regarding effects of LLLT on repairing MCL. [17][18][19] in their first study, tested the effects of a single dose of gallium-aluminum-arsenide (Ga-AlAr) laser on the strength of healing MCL in rats. Biomechanical analysis revealed ultimate tensile strength (UTS) and stiffness of laser group higher than control group.…”

Section: Introductionmentioning

confidence: 99%

“…They found UTS and stiffness of a single dose GaAlAr laser group higher than control group. 19 Fung et al suggested studying the effects of percutaneous laser therapy with multiple treatment sessions in order to simulate the normal clinical use of therapeutic laser. 19 Until now, there has been no knowledge pertaining to transmission electron microscope (TEM) study of a helium-neon laser on fibrils morphometry of repairing MCL.…”

Section: Introductionmentioning

confidence: 99%

“…19 Fung et al suggested studying the effects of percutaneous laser therapy with multiple treatment sessions in order to simulate the normal clinical use of therapeutic laser. 19 Until now, there has been no knowledge pertaining to transmission electron microscope (TEM) study of a helium-neon laser on fibrils morphometry of repairing MCL. The aim of the present study was to evaluate the effect of LLLT with a helium-neon laser on the fibrils diameter and their density of repairing MCLs in rats by TEM method.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effect of Low-Level Laser Therapy on Healing of Medial Collateral Ligament Injuries in Rats: An Ultrastructural Study

Delbari¹,

Bayat²,

Bayat³

2007

Photomedicine and Laser Surgery

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Combined Treatment of Therapeutic Laser and Herbal Application Improves the Strength of Repairing Ligament

Cited by 6 publications

References 43 publications

Using auriculotherapy for osteoarthritic knee among elders: a double-blinded randomised feasibility study

Using auriculotherapy for osteoarthritic knee among elders: a double-blinded randomised feasibility study

To evaluate the safety and efficiency of low level laser therapy (LLLT) in treating decubitus ulcers: a review

Effect of Low-Level Laser Therapy on Healing of Medial Collateral Ligament Injuries in Rats: An Ultrastructural Study

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