Combined tumour of aberrant cytokeratin expressing acral lentiginous melanoma and poroma: Diagnostic challenge

Sevim, Selim; Akay, Bengü Nisa; Kozan, Eda Nur; Heper, Aylin Okçu; Kirmizi, Ayca

doi:10.1111/ajd.14111

Cited by 1 publication

(1 citation statement)

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“…After radical removal, the prognosis of any form of poroma is favorable [ 5 ]. It can occur together with other skin lesions (eg, verruca plantaris and acral lentiginous melanoma), creating combined pathologies that are difficult to diagnose [ 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

Pigmented Poroma of the Lower Eyelid: A Case Report and Literature Review

Bogomolets,

Rojczyk,

Hryshchenko

et al. 2023

Am J Case Rep

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Patient: Female, 30-year-old Final Diagnosis: Eccrine poroma Symptoms: Fast growing eyelid lesion Clinical Procedure: Surgical excision Specialty: Dermatology Objective: Unusual clinical course Background: Eyelid tumors belong to a diverse group of neoplasms ranging from benign lesions to malignant tumors. Poromas are common, benign, mostly unpigmented tumors of the epidermal sweat duct unit, that usually grow slowly and occur in elderly people on the palms and soles. In most poroma cases some gene fusions were detected, which were caused by chromosomal aberrations. Case Report: We report the atypical case of a 30-year-old female patient suffering for more than 15 years from a solitary, polypoid, pigmented formation with a focal tuberous surface on the left lower eyelid. The lesion was not growing during the first years, but in the last 6 months before diagnosis its size more than doubled, finally reaching 12×14 mm. It was removed and histopathological analysis confirmed the diagnosis of a rare tumor – a poroma. There were no complications during healing and no recurrence was reported. Conclusions: There have so far been only 9 reports of eyelid poromas, and the presented case significantly differed from the previous ones, as it appeared at an early age and showed rapid growth during a short time due to the war-related acute psychological stress. Moreover, it had unusual pigmentation and unpleasant smell. Reporting such untypical cases is clinically important because it is crucial to be aware of the diversity of eccrine poroma manifestation to distinguish it from malignant lesions.

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Section: Introductionmentioning

confidence: 99%