Abstract-Good modeling, simulation, and analysis methods are essential elements of the systems engineering discipline and have become pervasive throughout the systems development lifecycle. Presently, a wide range of partially integrated Systems Engineering tools are available to the system architect, systems engineers, designers, developers, the production team, and system end-users. These tools are well vetted with industry and are capable of defining enterprise and systems architectures, integrating requirements management methodologies and helping drive the design to closure. Additionally, these tools establish a synergy that connects engineering, analysis, production, and support. These tools are ever-evolving as the systems engineering framework for systems development continues to expand its influence. At their most basic level, these tools provide an organized structure within which the conception, design, development, production, verification/validation, deployment, support, and even retirement of a system, service, product, or process may be executed. This "cradle-to-grave" scope lies at the core of the systems engineering lifecycle management philosophy. This paper presents the representative application of various systems engineering tools throughout the systems development lifecycle. Analysis, modeling and simulation methods and tools are used to evolve a system design and evaluate predicted system performance against established system requirements. An operational infrasound system is used to develop an example case study. This paper also presents the latest results of on-going research in the application of analysis and modeling tools to study man-made infrasound signals of interest (SOI).Index Terms-Infrasound, infrasound analysis, infrasound array, system modeling and analysis.