Combining machine learning with high-content imaging to infer ciprofloxacin susceptibility in clinical isolates of Salmonella Typhimurium
Stephen Baker,
Tuan-Anh Tran,
Sushmita Srid
et al.
Abstract:Antimicrobial resistance (AMR) is a growing public health crisis that requires innovative solutions. Presently we rely on exposing single organisms to an antimicrobial and growth to determine susceptibility; throughput and interpretation hinder our ability to rapidly distinguish between antimicrobial-susceptible and -resistant organisms isolated from clinical samples. Salmonella Typhimurium (S. Typhimurium) is an enteric pathogen responsible for severe gastrointestinal illness in immunocompetent individuals an… Show more
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