An optically accessible single-cylinder high speed direct-injection (HSDI) Diesel engine equipped with a Bosch common rail injection system was used to study low temperature Modulated Kinetics (MK) combustion with a retarded single main injection. High-speed liquid fuel Mie-scattering was employed to investigate the liquid distribution and evolution. By carefully setting up the optics, three-dimensional images of fuel spray were obtained from both the bottom of the piston and the side window. The NOx emissions were measured in the exhaust pipe. The influence of injection pressure and injection timing on liquid fuel evolution and combustion characteristics was studied under similar fuel quantities. Interesting spray development was seen from the side window images. Liquid impingement was found for all of the cases due to the small diameter of the piston bowl. The liquid fuel tip hits the bowl wall obliquely and spreads as a wall jet in the radial direction of the spray. Due to the bowl geometry, the fuel film moves back into the central part of the bowl, which enhances the airfuel mixing process and prepares a more homogeneous air-fuel mixture. Stronger impingement was seen for high injection pressures. Injection timing had little effect on fuel impingement. No liquid fuel was seen before ignition, indicating premixed combustion for all the cases. High-speed combustion video was taken using the same frame rate. Ignition was seen to occur on or near the bowl wall in the vicinity of the spray tip, with the ignition delay being noticeably longer for lower injection pressure and later injection timing. The majority of the flame was confined to the bowl region throughout the combustion event. A more homogeneous and weaker flame was observed for higher injection pressures and later injection timing. The combustion structure also proves the mixing enhancement effect of the liquid fuel impingement. The results show that ultralow sooting combustion is feasible in an HSDI diesel engine with a higher injection pressure, a higher EGR rate, or later injection timing, with little penalty on power output. It was also found that injection timing has more influence on HCCI-like combustion using a single main injection than the other two factors studied. Compared with the base cases, simultaneous reductions of soot and NOx were obtained by increasing EGR rate and retarding injection timing. By increasing injection pressure, NOx emissions were increased due to leaner and faster combustion with better air-fuel mixing. However, smoke emissions were significantly reduced with increased injection pressure.