The paper is concerned with identification of the key mechanisms controlling deflagration-todetonation transition in stellar medium. The issue of thermal runaway triggered by positive feedback between the advancing flame and the flame-driven precompression is discussed in the framework of a one-dimensional flame-folding model. The paper is an extension of the authors' previous study dealing with the non-stoichiometric fusion, f uel → products, kinetics (Phys.Rev.E, 103( 2021)) over physically more relevant, f uel + f uel → products, kinetics. Despite this change the runaway effect endures. The transition occurs prior to merging of the flame with the flame-supported precursor shock, i.e. the pretransition flame does not reach the threshold of Chapman-Jouguet deflagration.