Partially premixed combustion has the merits of lower NO x emission as well as higher efficiency. However practical applications of such technology have been hindered by acoustic instabilities generated in combustion chambers when gas turbine engines are operated in premixed mode. A thorough understanding of the physical processes which trigger and sustain this instability needs to be gained to aid the design of next generation low-emission high-efficiency gas turbine engines. In this work, acoustic instabilities manifested in the Gas Turbine Model Combustor (GTMC), which was developed at DLR Stuttgart by W. Meier and colleagues, were investigated. Specifically, the GTMC was operated with dimethyl ether (DME) in a fuel rich condition. Multi-point pressure measurements were carried out to characterize the dominant instability mode of the combustion chamber. Simultaneous Planar Laser-Induced Fluorescence (PLIF) of formaldehyde (CH 2 O) and pressure measurements were then made at a sustained frequency of 4 kHz. Flame surface densities, calculated from the flame edges detected in the PLIF images, were used as the indicator of flame heat release rate and determined both temporally and spatially. Finally a reduced order model was proposed to describe the observed combustion instability. Key predictions made by this model, such as instability frequency and pressure phase differences, agreed with experimental observations. Future work will focus on expanding present model to explore the effects of varying parameters on the combustion instability.