First of all, I would like to express my deepest gratitude to my main supervisor, Prof. Liu Yu. This research could not be fulfilled without his insightful guidance and prudent supervision. His profound knowledge and personal experiences not only encourage me to work harder on my research topic but also inspire and encourage me to be an open-minded researcher, and critical thinker. He always enlightens me to find logic ways to solve critical challenges in my research areas. Meanwhile, his rich life experience he shared with me always inspires me to find the truth of life. It is my great honor to be one of his students. I would also thank my co-supervisor, Prof. William Chen, and my mentor, Prof. Ng Wun Jern for their advice and supports. They are very friendly and approachable whenever I had any questions or difficulties during my PhD study.