This paper studies the rigidity properties of the abstract commensurator of the outer automorphism group of a universal Coxeter group of rank n, which is the free product W n of n copies of Z{2Z. We prove that for n Δ 5 the natural map OutpW n q Γ CommpOutpW n qq is an isomorphism and that every isomorphism between finite index subgroups of OutpW n q is given by a conjugation by an element of OutpW n q. 1