Comment on: “A Unique Clinicopathological Manifestation of Fungal Infection: A Case Series of Deep Dermatophytosis in Immunosuppressed Patients”

Erythematous Plaque Studded With Papules and Pustules in an Immunocompetent Patient

“…Although there is no standardized treatment for deep dermatophytosis, systemic antifungals such as terbinafine, fluconazole, and itraconazole have been reported to be efficacious. 4,9 Clinicians should remain suspicious of fungi as a potential cause of deep-tissue infection in both immunocompromised and immunocompetent patients. Fungal culture or polymerase chain reaction should be performed to confirm pathogen speciation.…”

“…Oftentimes, lymphocytes show irregular nuclear contours and may display cerebriform or convoluted nuclei, which were not seen in the histopathology of the present patient. Although there is no standardized treatment for deep dermatophytosis, systemic antifungals such as terbinafine, fluconazole, and itraconazole have been reported to be efficacious . Clinicians should remain suspicious of fungi as a potential cause of deep-tissue infection in both immunocompromised and immunocompetent patients.…”