“…Consequently, it poses a great challenge to trap viruses using optical tweezers. , Nonetheless, recent research indicates that the optical trapping force model for Rayleigh particles is primarily linked to the real part of polarizability. Quantum dots, often used as fluorescence labels for biomolecules, have the capability to augment the polarizability of particle surfaces. − Here, we built an optical tweezers system coupled with a laser confocal fluorescence imaging system, which can fluorescently image and trap the viruses in the culture medium in real time. , Under these conditions, we harnessed this technology to achieve fluorescence imaging of viruses and obtain trap stiffness. Here, we built an optical tweezers system coupled with a laser confocal fluorescence imaging system, which can fluorescently image and trap the viruses in the culture medium in real time. − At the same time, we also measured the trap stiffness of the modified viruses and obtained the same results.…”