Comment on “Multiple Independent Binding Sites for Small-Molecule Inhibitors on the Oncoprotein c-Myc”

Drug and dye binding induced folding of the intrinsically disordered antimicrobial peptide CM15

“…As such, these are induced (extrinsic) CD effects associated to the interaction between the chiral peptide and the achiral ligand. 26 Encoded by its structure, pamoic acid has a pronounced tendency to conformational enantiomerism induced by asymmetric hosts. 27,28 Interestingly, considered as a pharmacologically inactive constituent, pamoic acid has long been used in several drug formulations as pamoate salt.…”