Comment on “Role of monocyte to high-density lipoprotein cholesterol ratio in predicting left atrial enlargement in hypertensive patients”

Abstract

Dear editor,We are pleased to read the article published by Celik and Karaaslan 1 entitled "Role of monocyte to high-density lipoprotein cholesterol ratio in predicting left atrial enlargement in hypertensive patients". The results of this study revealed that the increased monocyte-tohigh-density lipoprotein cholesterol ratio level was associated with hypertension and increased left atrial volume indexes. This study may provide new information on the prevention measure to hypertensive patients with left atrial enlargement. However, according to our opinion, some concerns should be raised.The main concern is that baseline was inconsistent across two groups (Table 1). The monocyte-to-high-density lipoprotein cholesterol ratio may be increased with age. We found that the mean age in hypertension group was higher than that in the control group (53.1 years vs. 44.8 years). Thus, the age may be a confound factor that has an influence on the relationship between monocyte-to-high-density lipoprotein cholesterol