Commentary: Ocular lesions in leprosy – Should we forget?

Biswas, Jyotirmay; Pradhan, Arkaprava

doi:10.4103/ijo.ijo_186_22

Cited by 3 publications

(4 citation statements)

References 10 publications

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“…[ 28 ] The first two cases of ocular lesions in AIDS in India were reported in 1995. [ 29 ] In the late 1990s and early 2000s, a study on ocular associations with HIV in 100 consecutive cases found that over 40% of these patients had one or more ocular lesions, and various ocular lesions in AIDS patients were described. [ 30 ] Case reports started noting different associations between HIV and other disease entities like Cytomegalovirus (CMV), TB, and toxoplasmosis.…”

Section: Clinical Research In Uveitismentioning

confidence: 99%

Evolution of research in diagnosis and management of uveitis over four decades in India

Biswas,

Jadhav,

Eswaran

2024

Indian Journal of Ophthalmology

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Uveitis and its complications are more common in the developing world, in which the condition occurs in up to 714 per 100,000 in the population and accounts for up to 25% of all blindness. In India, the ophthalmic sub speciality of uveitis greatly evolved in the last four decades. In the early decades most of the studies were epidemiological studies. In recent years, more research has been published due to tremendous advancements in clinical diagnosis, laboratory investigations and ancillary test and treatment modalities. In this review article, we did a medline search with key words ‘uveitis’ and ‘India’, and selectively incorporated articles showing the evolution of this sub-speciality in India.

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Section: Clinical Research In Uveitismentioning

confidence: 99%

Evolution of research in diagnosis and management of uveitis over four decades in India

Biswas,

Jadhav,

Eswaran

2024

Indian Journal of Ophthalmology

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“…1 127,558 new cases were reported globally from 139 countries in 2020. 2 India has the highest incidence of leprosy with the current prevalence rate being 0.57/10,000 population. 2 Ocular involvement occurs in 70-75% of patients afflicted with leprosy and blindness occurs in 5%.…”

Section: Introductionmentioning

confidence: 99%

“…2 India has the highest incidence of leprosy with the current prevalence rate being 0.57/10,000 population. 2 Ocular involvement occurs in 70-75% of patients afflicted with leprosy and blindness occurs in 5%. 3 The sequelae in ocular leprosy are lagophthalmos, paralytic ectropion, entropion, Correspondence to: Lily Dhaya Daniel (Tel.…”

Section: Introductionmentioning

confidence: 99%

A satisfactory visual outcome following sequential oculoplastic procedures and small incision cataract surgery in an elderly patient with severe sequelae of ocular leprosy – A case report

Daniel,

Bahkir

2023

LEPROSY

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The ocular manifestations of Hansen's Disease (HD) are myriad and the sequelae of ocular leprosy often lead to severe visual compromise. Cataract surgery in such a patient is often not done immediately, as would normally be expected in the world today. The management of other sequelae have to be addressed before embarking on the management of cataract. We report the successful management of an elderly patient, a treated case of HD who presented with bilateral lagophthalmos, paralytic ectropion, punctal obliteration, diminished corneal sensation, exposure keratitis and bilateral cataract. He underwent bilateral sequential oculoplastic and lacrimal procedures followed by small incision cataract surgery (SICS) in the eye with lesser corneal scarring and had a very satisfactory visual outcome in that eye. Paralytic ectropion in HD when associated with diminished corneal sensation requires adequate and early tarsorraphy to prevent exposure keratitis and subsequent corneal scarring. This simple oculoplastic procedure would go a long way in preserving useful vision in a patient afflicted by HD.

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“…[ 3 ] Ocular lesions in AIDS patients in India were first reported in 1995. [ 4 ] Ocular manifestations in AIDS include both anterior and posterior segments of the eye. Most of the manifestations are those of the posterior segment, like HIV retinopathy, opportunistic infections, neuro-ophthalmic lesions, and unusual neoplasms.…”

mentioning

confidence: 99%

Ocular manifestations in HIV patients attending a tertiary care hospital in Eastern India and correlation of posterior segment lesions with CD4+ counts

Swain,

Sharma,

Mohanty

et al. 2023

Indian Journal of Ophthalmology

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Purpose: We aimed to study the ocular manifestations in human immunodeficiency virus (HIV)-infected patients and the correlation of posterior segment lesions with CD4+ counts. Methods: This hospital-based, cross-sectional study enrolled HIV-positive patients attending the ophthalmology department of a tertiary care hospital in Eastern India. Complete demographic information was obtained for each patient. Comprehensive ophthalmic evaluation was done in each case. Results: A total of 184 HIV-positive patients were enrolled in the study. Ocular manifestations were detected in 62 cases. The prevalence of ocular manifestations in the present study was 33.69%. Mean age of patients included in the study was 34.8 ± 10.77 years. Prevalence of ocular manifestations was highest in the age group of 30–39 years (41.93%). Highest prevalence of ocular manifestations was noted in patients with low level of education and poor socioeconomic status. Sexual transmission was the major route of HIV transmission (in 92% of cases). Posterior segment lesions were seen in 69.35% of cases. HIV retinopathy was the most common posterior segment manifestation noted in 25 eyes. Significant positive correlation was noted between severities of posterior segment findings and CD4+ counts, which we found to increase with decrease in CD4+ counts (P < 0.001). Conclusion: Detailed ophthalmic evaluation including fundus examination is must in all cases of HIV/acquired immunodeficiency syndrome (AIDS) patients as it may help in early diagnosis, treatment, and prevention of sight-threatening complications due to opportunistic infections.

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Commentary: Ocular lesions in leprosy – Should we forget?

Cited by 3 publications

References 10 publications

Evolution of research in diagnosis and management of uveitis over four decades in India

Evolution of research in diagnosis and management of uveitis over four decades in India

A satisfactory visual outcome following sequential oculoplastic procedures and small incision cataract surgery in an elderly patient with severe sequelae of ocular leprosy – A case report

Ocular manifestations in HIV patients attending a tertiary care hospital in Eastern India and correlation of posterior segment lesions with CD4+ counts

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