Commentary on cellulite: skin mechanobiology and the waist‐to‐hip ratio

Pierard, Gérald

doi:10.1111/j.1473-2165.2005.00302.x

Cited by 23 publications

(25 citation statements)

References 12 publications

(23 reference statements)

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“…Some strands are enlarged and fi brosclerotic, whereas other strands become loose. At the latter sites, edema and deposits of proteoglycans may be present in association with alterations in the shape and pattern of distribution of the elastic fi bers [ 26 ] .…”

Section: Anatomical Considerationsmentioning

confidence: 99%

“…Cellulite is viewed as the result of a combination of the gender-related dimorphism of the hypodermal tissue and mechanobiological effects of tissue tensions inside this tissue, being thus much more prevalent in women than in men [ 26 ] .…”

Section: Anatomical Considerationsmentioning

confidence: 99%

“…The standing lobules, called papillae adipose, rise into pits and dells at the surface of the dermis [ 26 ] .…”

Section: Anatomical Considerationsmentioning

confidence: 99%

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Cellulite

Hexsel

Mazzuco²

2013

Update in Cosmetic Dermatology

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Elements that seem to be involved in cellulite's appearance are: adipocyte • hypertrophy, connective tissue abnormalities, fi brous septa, and hormonal in fl uences.A new cellulite severity scale (CSS) and classi fi cation was recently devel-• oped. The CSS considers relevant morphological aspects, such as the number of evident depressions, depth of depressions, aspect of raised areas, grade of laxity, fl accidity or sagging skin, and the previous cellulite scale. Diagnosis is mainly clinical although magnetic resonance imaging, laser • Doppler fl owmetry, thermography, and ultrasound can be used for research purposes.A series of treatments can treat or improve the appearance of cellulite, such • as topical products, oral supplements, devices (mechanical massage, lasers, light sources, radiofrequency, and other technologies), and surgical procedures (Subcision ® and liposuction).

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Section: Anatomical Considerationsmentioning

confidence: 99%

Section: Anatomical Considerationsmentioning

confidence: 99%

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Cellulite

Hexsel

Mazzuco²

2013

Update in Cosmetic Dermatology

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“…L'ensemble de ces phénomènes conduit à l'apparition de l'aspect bien connu de « peau d'orange » sur les fesses, les cuisses, les hanches et le ventre [4][5][6].…”

Section: Introductionunclassified

“…La seconde principale cause de l'apparition de la cellulite est liée au développement d'une fibrose du tissu conjonctif, conséquence de l'évagination des lobules graisseux dans le derme [5,6]. En effet, lorsque soumis à des changements de pression, les cellules graisseuses doivent adapter leur forme sans modifier leur volume.…”

Section: Introductionunclassified

Étude clinique d’une SuperOxide Dismutase de melon naturelle et bioactive (SOD B Dimpless®) sur la cellulite

Lemaire

Quéré

Simoneau³

et al. 2015

Phytothérapie

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Une étude clinique, randomisée en double aveugle contre placebo, a été conduite sur 41 femmes ayant de la cellulite, âgées de 31 à 50 ans. 21 d'entre elles ont été supplémentées oralement avec SOD B Dimpless ® , un jus de melon séché hautement concentré en SuperOxyde Dismutase (SOD), à 40 mg par jour (480 IU SOD) pendant 56 jours consécutifs. La cellulite a été mesurée par l'éva-luation visuelle des capitons graisseux sur le ventre et les cuisses, à l'aide d'une échelle linéaire. La supplémentation orale avec SOD B Dimpless ® a significativement réduit la cellulite sur les cuisses en comparaison avec le groupe placebo après 28 jours. Cette réduction est amplifiée après 56 jours de supplémentation. Le mécanisme d'action pourrait impliquer l'induction de l'expression des enzymes antioxydantes endogènes, conduisant à l'inhibition de la fibrose et à la stimulation de la lipolyse. D'autres investigations sont nécessaires afin de confirmer le mode d'action de SOD B Dimpless ® contre la cellulite. Mots clés Stress oxydant · Enzymes antioxydantes · Fibrose · LipolyseAbstract A randomized, double blind, placebo controlled clinical study was conducted on 41 women with cellulite aged between 31 and 50 years old. 21 of these were orally supplemented with SOD B Dimpless ® , a natural dry melon juice highly concentrated in SuperOxide Dismutase (SOD) at 40 mg per day (480 IU SOD), during 56 consecutive days. Cellulite was measured visually by scoring fat nodes on stomach and thighs, according to a linear scale. The oral supplementation with SOD B Dimpless ® significantly reduced cellulite on thighs compared to the placebo after 28 days. This reduction is amplified after 56 days of supplementation. The mechanism of action may involve the induction of endogenous antioxidant enzymes expression, leading to the inhibition of fibrosis and the stimulation of lipolysis. Further investigations are necessary to document the way of action of SOD B Dimpless ® against cellulite.

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Cellulite: Etiology and Treatment

Vicente-Ruiz

2023

Post-Maternity Body Changes

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Commentary on cellulite: skin mechanobiology and the waist‐to‐hip ratio

Cited by 23 publications

References 12 publications

Cellulite

Cellulite

Étude clinique d’une SuperOxide Dismutase de melon naturelle et bioactive (SOD B Dimpless®) sur la cellulite

Cellulite: Etiology and Treatment

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