Commentary on Systematic Review of Intensity Modulated Brachytherapy (IMBT): Static and Dynamic Techniques

Song, William Y.; Enger, Shirin A.

doi:10.1016/j.ijrobp.2019.07.050

Cited by 3 publications

(2 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Additionally, moving shields in direction-modulated brachytherapy are used with Ir-192 and a rotating tungsten cylinder for treating rectal cancer (ICRP 2002). As a result, many static and dynamic approaches are used with IMBT, which have shown to produce better target coverage and decreased dose to normal tissues (Song and Enger 2019). Also, there has been an increase in three-dimensional image guided brachytherapy, which has increased the demand for new applicators (Song and Enger 2019).…”

Section: Introductionmentioning

confidence: 99%

“…As a result, many static and dynamic approaches are used with IMBT, which have shown to produce better target coverage and decreased dose to normal tissues (Song and Enger 2019). Also, there has been an increase in three-dimensional image guided brachytherapy, which has increased the demand for new applicators (Song and Enger 2019). Patient care may be improved through technological innovations therefore, developing new IMBT approaches is essential for the advancement of the field.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Shielded high dose rate ocular brachytherapy using Yb-169

Dupere¹,

Munro²,

Medich³

2021

Phys. Med. Biol.

View full text Add to dashboard Cite

Purpose. We propose an approach for treating ocular melanoma using a new type of brachytherapy treatment device. This device couples Yb-169, a middle-energy high dose rate (HDR) brachytherapy source, with a gold shielded ring applicator to better conform radiation exposures to the tumor. In this study, we computationally test the dosimetric output of our proposed shielded ring applicator design using MCNP6 and validate it against an I-125 COMS plaque. Methods. The proposed Yb-169 ring applicator consists of an assembly of discrete sources delivered into an applicator with a conical collimated opening; this opening is tangent to the outside of the source tube. Using MCNP6, we simulated the dosimetric output of a ring of Yb-169 pellets placed within the collimator at various conical diameters and angles to demonstrate the dosimetric distribution for various prescription dose depths and target sizes using static intensity modulation. Results. Using various angles of collimation, the prescription dose was delivered to target apex depths of 3.5–8.0 mm into the eye covering target sizes ranging from 10 to 15 mm in diameter. This proposed device reduced the maximum absorbed dose to critical structures relative to I-125 by 5.2% to the posterior lens, 9.3% to the iris, 13.8% to the optic nerve, and 1.3% to the sclera. Conclusions. This proposed eye plaque design provides a more conformal dose distribution to the ocular tumor while minimizes dose to healthy ocular structures. In addition, the use of a middle-energy HDR brachytherapy source allows the use of a remote afterloader to expose the tumor after the plaque is sutured in place. This system is inherently safer and eliminates dose to the surgeon’s hands.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Shielded high dose rate ocular brachytherapy using Yb-169

Dupere¹,

Munro²,

Medich³

2021

Phys. Med. Biol.

View full text Add to dashboard Cite

show abstract

169Yb-based high dose rate intensity modulated brachytherapy for focal treatment of prostate cancer

Robitaille,

Ménard,

Famulari

et al. 2024

Brachytherapy

View full text Add to dashboard Cite

Brachytherapy: A Comprehensive Review

Lim

Doh-Yeon

2021

Progress in Medical Physics

View full text Add to dashboard Cite

Brachytherapy, along with external beam radiation therapy (EBRT), is an essential and effective radiation treatment process. In brachytherapy, in contrast to EBRT, the radiation source is radioisotopes. Because these isotopes can be positioned inside or near the tumor, it is possible to protect other organs around the tumor while delivering an extremely high-dose of treatment to the tumor. Brachytherapy has a long history of more than 100 years. In the early 1900s, the radioisotopes used for brachytherapy were only radium or radon isotopes extracted from nature. Over time, however, various radioisotopes have been artificially produced. As radioisotopes have high radioactivity and miniature size, the application of brachytherapy has expanded to high-doserate brachytherapy. Recently, advanced treatment techniques used in EBRT, such as image guidance and intensity modulation techniques, have been applied to brachytherapy. Threedimensional images, such as ultrasound, computed tomography, magnetic resonance imaging, and positron emission tomography are used for accurate delineation of treatment targets and normal organs. Intensity-modulated brachytherapy is anticipated to be performed in the near future, and it is anticipated that the treatment outcomes of applicable cancers will be greatly improved by this treatment's excellent dose delivery characteristics.

show abstract

Commentary on Systematic Review of Intensity Modulated Brachytherapy (IMBT): Static and Dynamic Techniques

Cited by 3 publications

References 8 publications

Shielded high dose rate ocular brachytherapy using Yb-169

Shielded high dose rate ocular brachytherapy using Yb-169

169Yb-based high dose rate intensity modulated brachytherapy for focal treatment of prostate cancer

Brachytherapy: A Comprehensive Review

Contact Info

Product

Resources

About