Commercial Lentils (Lens culinaris) Provide Antioxidative and Broad-spectrum Anti-cancerous Effects

Kiran, Shashi; Johnson, Joel B.; Mani, Janice S.; Portman, Andrew; Mizzi, Trent; Naiker, Mani

doi:10.18805/lr-557

Cited by 4 publications

(4 citation statements)

References 19 publications

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“…Lentils have different groups of phenolic compounds acting as antioxidants, due to their ability to reduce the formation of reactive oxygen species, such as the superoxide anion, by chelating metal ions or inhibiting enzymes [ 79 , 80 ]. Among these, the most important are procyanidin and prodelphinidin dimers and trimers, gallate procyanidins, kaempferol derivatives, quercetin glucoside acetate, luteolin derivatives and p-coumaric acid, hydroxybenzoic compounds, protocatechuic, vanillic acid, aldehyde p-hydroxybenzoic, trans-ferulic acid and trans-p-coumaric acid.…”

Section: Health Benefits Of Lentils Polyphenolsmentioning

confidence: 99%

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Polyphenols, Saponins and Phytosterols in Lentils and Their Health Benefits: An Overview

et al. 2022

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The lentil (Lens culinaris L.) is one of the most important legumes (family, Fabaceae). It is a natural functional food rich in many bioactive compounds, such as polyphenols, saponins and phytosterols. Several studies have demonstrated that the consumption of lentils is potentially important in reducing the incidence of a number of chronic diseases, due to their bioactive compounds. The most common polyphenols in lentils include phenolic acids, flavan-3-ol, flavonols, anthocyanidins, proanthocyanidins or condensed tannins, and anthocyanins, which play an important role in the prevention of several degenerative diseases in humans, due to their antioxidant activity. Furthermore, lentil polyphenols are reported to have antidiabetic, cardioprotective and anticancer activities. Lentil saponins are triterpene glycosides, mainly soyasaponins I and βg. These saponins have a plasma cholesterol-lowering effect in humans and are important in reducing the risk of many chronic diseases. Moreover, high levels of phytosterols have been reported in lentils, especially in the seed coat, and β-sitosterol, campesterol, and stigmasterol are the most abundant. Beyond their hypocholesterolemic effect, phytosterols in lentils are known for their anti-inflammatory activity. In this review, the current information on the nutritional composition, bioactive compounds including polyphenols, saponins and phytosterols, and their associated health-promoting effects are discussed.

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Section: Health Benefits Of Lentils Polyphenolsmentioning

confidence: 99%

“…Lentil seeds reduce the influence of colon, thyroid, liver, breast and prostate cancers [ 80 , 87 ]. An epidemiological study on 90,630 women demonstrates that the consumption of polyphenol-rich lentils reduces the risk of breast cancer.…”

Section: Health Benefits Of Lentils Polyphenolsmentioning

confidence: 99%

Polyphenols, Saponins and Phytosterols in Lentils and Their Health Benefits: An Overview

et al. 2022

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“…Additionally, lentils contain several groups of phenolic compounds, which act as antioxidants. These antioxidant groups have the ability to suppress the formation of many reactive oxygen species (ROS) (23,24).…”

Section: Introductionmentioning

confidence: 99%

Grain nutritional and antioxidant profiling of diverse lentil (Lens culinaris Medikus) genetic resources revealed genotypes with high nutritional value

Riaz,

Hameed,

Asghar

2024

Front. Nutr.

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The lentil (Lens culinaris Medikus ssp. Culinaris) is a self-pollinating, diploid (2n = 2X = 14) crop with a genome size of 4 Gbp. The present study was conducted to provide a database for the evaluation of lentil antioxidant capacity, nutritional quality, and biochemical attributes. For these purposes, lentil germplasm, including 100 exotic and local genotypes from different agro-climatic zones of Pakistan, was collected. Significant variation (p < 0.05) was found among the genotypes under investigation using the Tukey HSD test. Ascorbate peroxidase was highest in ALTINOPARK (2,465 Units/g s. wt.), catalase in LPP 12110 (5,595 Units/g s. wt.), superoxide dismutase in LPP 12105 (296.75 Units/g s. wt.), and peroxidase in NIAB Masoor 2002 (3,170 Units/g s. wt.). Furthermore, NLM 15016 had a maximum total antioxidant capacity of 15.763 mg/g s. wt. The maximum values of total soluble sugars (83.93 mg/g. s. wt.) and non-reducing sugars (74.79 mg/g. s. wt.) were noticed in NLM 15015. The highest reducing sugars were detected in ILL 8006 (45.68 mg/g. s. wt.) ascorbic acid in LPP 12182 (706 μg/g s. wt.), total phenolic content in NLI 17003 (54,600 μM/g s. wt.), and tannins in NLI 17057 (24,563 μM/g s. wt.). The highest chlorophyll a (236.12 μg/g s. wt.), chlorophyll b (317 μg/g s. wt.), total chlorophyll (552.58 μg/g s. wt.), and lycopene (10.881 μg/g s. wt.) were found in NLH 12097. Maximum total carotenoids were revealed in the local approved variety Markaz 2009 (17.89 μg/g s. wt.). Principal component analysis (PCA), correlation analysis (Pearson’s test), and agglomerative hierarchical clustering (AHC) were performed to detect the extent of variation in genotypes. In cluster analysis, all genotypes were categorized into three clusters. Cluster II genotypes showed remarkable divergence with cluster III. According to PCA, the contribution of PC-I regarding tested nutritional parameters toward variability was the highest (39.75%) and indicated positive factor loading for the tested nutritional and biochemical parameters. In conclusion, genotype X 2011S 33–34-32 can be used by the food industry in making pasta, multigrain bread, and snacking foods due to its high protein content for meat alternative seekers. Identified genotypes with high nutritional attributes can be utilized to improve quality parameters in the respective lentil breeding lines.

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“…Antioxidants are a large group of compound which is formed of enzymes, vitamins, some metals and they may prevent oxidative damage in the cell due to free radicals (Senel et al, 2018). Oxidative stress arises from malfunctioning internal antioxidant processes leading to range of pathophysiological conditions, primarily neurodegenerative disorders, biological aging and cancer (Kiran et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

Phytochemical Content, Antioxidant and Antimicrobial Effects of Thapsia garganica L. Leaves and Roots Grown Wild in North-west Algeria

Djahida

Benmehdi

2021

IJARe

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Background: Oxygen-centre free radicals and other reactive oxygen species (ROS) are continuously produced in vivo, resulting in cell death and tissues damage. Besides, the increasing resistance to existing antimicrobial agents has become a major problem. The present study aims to evaluate the antioxidant and antimicrobial activities of the Thapsia garganica L. leaves and roots. Methods: Broth dilution and single spore methods were developed and seven microorganisms were used. The evaluation was performed by measuring the diameter of the growth inhibition zones around the holes via the determination of the inhibition percentage of mycelium growth. Result: The determination of the polyphenol contents, total flavonoids and condensed tannins of the aqueous extract for both leaves and roots gave respectively (2.21 mg, 2.63 mg/100 mg gallic acide equivalents), (2.39 mg, 0.49 mg/100 mg catechin equivalent), (0.12 mg, 0.04 mg/100 mg catechin equivalent) in dry matter. The results of antioxidant activity showed that the methanolic, flavonoids and tannins extracts showed a potent scavenging activity with IC50 = 0.41; 0.81; 1.39; 1.80 and 1.90 mg/ml, respectively. As regards for antimicrobial activity, an important inhibition of the proposed extracts has been observed against the tested strains.

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Commercial Lentils (Lens culinaris) Provide Antioxidative and Broad-spectrum Anti-cancerous Effects

Cited by 4 publications

References 19 publications

Polyphenols, Saponins and Phytosterols in Lentils and Their Health Benefits: An Overview

Polyphenols, Saponins and Phytosterols in Lentils and Their Health Benefits: An Overview

Grain nutritional and antioxidant profiling of diverse lentil (Lens culinaris Medikus) genetic resources revealed genotypes with high nutritional value

Phytochemical Content, Antioxidant and Antimicrobial Effects of Thapsia garganica L. Leaves and Roots Grown Wild in North-west Algeria

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