Common carotid intima-media thickness in acute ischemic stroke: A case control study

Abstract

Stroke is the third leading cause of mortality worldwide. Combined carotid intima-media thickness (CIMT) is a marker of atherosclerosis and is also a predictor for ischemic stroke. We determined the frequency of CIMT in patients with acute ischemic stroke and in matched controls and also the risk factors for CIMT. Sixty patients with ischemic stroke diagnosed by computer tomography (CT) scan and 50 controls matched by age, gender, diabetes, and hypertension were studied. Subjects in both groups underwent carotid duplex scanning (ACUSON 128 x P/10 machine) with a 7.5 MHz linear superficial array probe in B-mode to determine the CIMT and presence of plaques. The mean age in the patient group was 62 years and 63.3% were males. The average CIMT in the patient group was 0.798 mm and it was 0.6 mm in the control group (P < 0.0001). Patients with carotid plaque had significantly increased IMT (0.95 +/- 0.22) when compared to patients without plaques (0.71 +/- 0.12) (P < 0.001). When the differences in mean IMT were compared among the different age groups in the patient group, there was significance (P < 0.05). In this study the CIMT was independently associated with increasing age and with the presence of carotid plaques.

Carotid Doppler Evaluation of Transient Ischemic Attack And Stroke Patients And Its Correlation With CT Scan Head: A Prospective Study

“…It is believed that thickening of the intima media thickness complex greater than 0.8 mm is abnormal and may represent the earliest changes of atherosclerotic disease (9) .The mean intima media thickness in TIA and stroke patients was 1.1 mm and 0.82 mm respectively. The results showed that mean intima media thickness in our study was slightly greater than that found by Ratnakar Sahoo et al (2009) (10) , where it was 0.78 mm (range 0.5-1.5 mm) in patient group and 0.594 mm (range 0.4-0.9 mm) in controls. In this study 73% and 84% of patients showed evidence of plaques in transient ischaemic attack and stroke group of patients respectively.…”

Carotid Intima Media Thickness in Patients With Acute Ischaemic Stroke

“…In the study by Sahoo R et al (1) carotid plaques were present in 18 (30%) patients with stroke and 7 (14%) in controls similar to our study, which showed carotid plaques in 17 cases and 6 controls. In the study by Nikic P et al, (3) there was a significant difference in the distribution of plaque status between cases and controls.…”

“…While, in the study by Sahoo R et al, (1) the mean carotid intima media thickness in the patient group was 0.782 ± 0.19 mm and 0.594 ± 0.98 mm in control group. Our study showed a higher mean carotid intima media thickness when compared to the above study.…”

“…The mean age among cases were 62.7 ± 8.5 and controls were 52.7 ± 6.9. In a similar study by Sahoo et al, (1) 60 patients and 50 controls were studied. The mean age in the patient group was 62 years and 63.3% were males.…”

Carotid artery intima media thickness in relation with atherosclerotic risk factors in patients with newly diagnosed type 2 diabetes mellitus in a rural tertiary care hospital in central India

“…Doruk et al noticed that there was no significant correlation between age and carotid artery IMT. 16 On the other hand Robin et al reported that IMT was independently and positively related to age. 17 It was also observed that the IMT increased with the duration of diabetes with a significant p value of 0.0218.…”