Common carotid intima–media thickness is correlated with myocardial flow reserve in patients with coronary artery disease: a useful non-invasive indicator of coronary atherosclerosis

Sonoda, Makoto; Yonekura, Katsunori; Yokoyama, Ikuo; Takenaka, Katsu; Nagai, Ryozo; Aoyagi, Takaaki

doi:10.1016/s0167-5273(03)00125-6

Cited by 29 publications

(20 citation statements)

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“…2,11) Epidemiological studies have showed that increased CCA-IMT was correlated with known cardiovascular risk factors and was associated with an increased prevalence and incidence of cardiovascular disease. 12,13) Confirming data in the literature, we found that the CCA-IMT increased with age and serum ferritin levels.…”

Section: Discussionmentioning

confidence: 99%

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<b>Intravenous Iron Therapy as a Possible Risk Factor for Atherosclerosis in End-stage Renal Disease</b>

et al. 2005

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SUMMARYAtherosclerosis is a disease of the arterial wall, with increasing wall thickness representing an early event in the progression of the disease. It has been suggested that iron overload, as assessed by increased serum ferritin concentration, may be a risk factor for atherosclerosis.The aim of this study was to investigate the relationship between the influence of intravenous (IV) iron therapy and ferritin levels and carotid intima media thickness (C-IMT) in dialysis patients. Sixty patients (51 ± 14) years were divided into two groups according to their IMT obtained by ultrasound; group I (high risk) and group II (low risk). The parameters assessed were serum creatinine, urea, calcium, phosphorus, hemoglobin, albumin, uric acid, iron, ferritin, and lipid levels. Thirty-eight patients (88%) in group I and 5 patients (12%) in group II received IV iron therapy while 5 patients (29%) in group I and 12 patients (71%) in group II (P < 0.001) did not receive IV iron therapy. Ferritin levels were higher in group I than in group II (581 ± 303 and 306 ± 224) (P < 0.001). C-IMT measurements correlated with serum ferritin and with the intravenous iron dose received during the 24 months preceding the study (r = 0.315, P = 0.015; r = 0.471, P = 0.001).The findings indicate that IV iron therapy and elevated serum ferritin levels may cause an increase in the incidence of atherosclerosis. (Int Heart J 2005; 46: 255-264)

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Section: Discussionmentioning

confidence: 99%

“…2) There are several risk factors whose association with atherosclerosis is well established, including age, gender, lipid disorders, smoking, hypertension, diabetes mellitus, obesity, and lifestyle.…”

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<b>Intravenous Iron Therapy as a Possible Risk Factor for Atherosclerosis in End-stage Renal Disease</b>

et al. 2005

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“…Rotterdam's study [12] revealed that carotid ultrasound findings were a new indicator of myocardial infarction after cardiovascular mortality in healthy adults over 55 years of age. Ogata et al [13] investigated the relationship between IMT and the left main transthoracic calcification, and Sonoda et al [14] presented their findings for coronary blood flow and IMT. Both studies reported a high IMT value to be a good indicator of the extent of CAD.…”

Section: Discussionmentioning

confidence: 99%

Association between Carotid Artery Plaque Score and SYNTAX Score in Coronary Artery Disease Patients

Chung¹

2017

Gen Med

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Background: Numerous studies have been published the correlation between plaque score (PS), mean carotid artery intima-media thickness (IMT), and the prevalence or complexity of coronary artery lesions in coronary artery disease (CAD) patients. However, very few studies have reported the association between the complexity of coronary artery lesions and PS and the mean carotid artery IMT. We therefore aimed to examine the correlation between carotid artery ultrasound parameters and complexity of coronary artery lesions in CAD patients.

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“…Firstly, it is already known that thickened intima is an indicator of reduced myocardial flow reserve 26 . This may be the result of coronary microvascular obstruction and/or reduced vasodilator reserve of epicardial vessels, due to endothelial dysfunction.…”

Section: Discussionmentioning

confidence: 99%

Influência da aterosclerose subclínica na função diastólica em indivíduos sem doença cardiovascular

Garcia

Rodrigues

Neto

et al. 2010

Arq. Bras. Cardiol.

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Common carotid intima–media thickness is correlated with myocardial flow reserve in patients with coronary artery disease: a useful non-invasive indicator of coronary atherosclerosis

Cited by 29 publications

References 20 publications

<b>Intravenous Iron Therapy as a Possible Risk Factor for Atherosclerosis in End-stage Renal Disease</b>

<b>Intravenous Iron Therapy as a Possible Risk Factor for Atherosclerosis in End-stage Renal Disease</b>

Association between Carotid Artery Plaque Score and SYNTAX Score in Coronary Artery Disease Patients

Influência da aterosclerose subclínica na função diastólica em indivíduos sem doença cardiovascular

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