Common Complications of Surgery for Crohn's Disease and Ulcerative Colitis

Li, Yi; Zhu, Weiming

doi:10.1016/b978-0-12-811388-2.00024-5

Cited by 4 publications

(4 citation statements)

References 120 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Current treatment options (e.g. surgery) do not reliably cure IBD and are often associated with undesirable side effects and complications (Hazel & O'Connor, 2020;Li & Zhu, 2018). Therefore, further understanding of the disease is required to enable the development of improved, alternative treatment options.…”

Section: Introductionmentioning

confidence: 99%

The effects of postbiotics on chemically-induced colitis in mice: A protocol for a systematic literature review and meta-analysis

Kleanthous,

Barrett,

Vinderola

et al. 2023

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

The effects of postbiotics on chemically-induced colitis in mice: A protocol for a systematic literature review and meta-analysis

Kleanthous,

Barrett,

Vinderola

et al. 2023

View full text Add to dashboard Cite

show abstract

“…Inflammatory bowel disease patients' experience more postoperative problems than those who have had other types of colon surgery, due to bad general condition, anemia, malnutrition, and immunosuppressant and anti-TNF use just before surgery. This might led to poor wound healing, leakage, and anastomotic stricture (Li and Zhu, 2018).…”

Section: Introductionmentioning

confidence: 99%

Depression and Anxiety Disorders in Surgically Managed Patients With Inflammatory Bowel Disease

RASHAD,

KAMEL,

ASKAR

et al. 2023

Journal of the Egyptian Society of Parasitology

View full text Add to dashboard Cite

Inflammatory bowel diseases are mainly treated medically, especially with the availability of biological agents, but surgery is recommended when medical treatment fails, as in ulcerative colitis, or when complications occur, as in Crohn's disease. Although IBD patients who underwent surgery had a better quality of life, they also had a higher risk of depression and anxiety than the general population. This study compared psychiatric morbidities regarding anxiety and depression in surgically managed IBD patients to nonsurgically managed patients.The anxiety and depression prevalence were determined in 105 IBD patients, including seven who underwent surgery, by performing a psychiatric interview using SCID I and assessing depression and anxiety severity using the Hamilton Depression Scale (HAM-D) and the Hamilton Anxiety Scale (HAM-A), respectively. Similarity in surgically and nonsurgically managed IBD patients might be due to small number of surgical patients.

show abstract

“…2 There is also evidence that men with IBD have worse outcomes compared to women, including higher rates of disease-related complications, 4 such as osteopenia, 5,6 some types of pancreatitis, 7 and colon cancer 8 ; hospital readmission after initial diagnosis 9 ; escalation of medical therapy 10 ; and need for surgical intervention. [11][12][13][14] Surgical complications are relatively more common in patients with IBD than in patients undergoing bowel surgery for other reasons and most commonly include wound infection and anastomotic complications 15 ; rates of wound infections have been reported to vary from 1% to 19% [16][17][18] and rates of anastomotic leak range from 0.5% to 13%. [16][17][18][19] Although it is fairly well established that men are more likely to require surgery for IBD, much less is known about the outcomes of surgery for men than women.…”

mentioning

confidence: 99%

“…Surgical complications are relatively more common in patients with IBD than in patients undergoing bowel surgery for other reasons and most commonly include wound infection and anastomotic complications 15 ; rates of wound infections have been reported to vary from 1% to 19% 16–18 and rates of anastomotic leak range from 0.5% to 13%. 16–19 Although it is fairly well established that men are more likely to require surgery for IBD, much less is known about the outcomes of surgery for men than women.…”

mentioning

confidence: 99%

Sex-Based Differences in Inflammatory Bowel Disease Surgical Outcomes

Sundel,

Newland,

Blackburn

et al. 2023

Diseases of the Colon &Amp; Rectum

View full text Add to dashboard Cite

BACKGROUND: Although there are discrepancies in the development and progression of inflammatory bowel disease based on biologic sex, little is known about differences in postoperative outcomes between men and women undergoing surgery for this condition. OBJECTIVE: Our objective was to compare rates of anastomotic leaks, wound complications, and serious adverse events between men and women undergoing surgery for inflammatory bowel disease. DESIGN: This was a retrospective cohort study. SETTINGS: Data were obtained from the American College of Surgeons National Surgical Quality Improvement Program Inflammatory Bowel Disease Collaborative database, which includes 15 high-volume inflammatory bowel disease surgery centers. PATIENTS: All adult patients undergoing surgery for inflammatory bowel disease were included. Subjects with missing data for exposure or outcome variables were excluded. MAIN OUTCOME MEASURES: Rates of anastomotic leaks, wound complications, and serious adverse events were compared between women and men. RESULTS: A total of 3143 patients were included. There was a significant association between sex and body mass index, inflammatory bowel disease type, and preoperative medication use. Women had decreased odds of serious adverse events compared to men (OR=0.73, 95% CI: 0.55-0.96), but there was no significant association between sex and anastomotic leaks or wound complications. Inflammatory bowel disease type was found to be an effect measure modifier of the relationship between sex and serious adverse events. Among ulcerative colitis patients, women had a 54% decrease in the odds of serious adverse events compared to men, while there was no significant difference between women and men with Crohn’s disease. LIMITATIONS: This study was limited by capturing only 30 days of postoperative outcomes. CONCLUSIONS: Women undergoing surgery for ulcerative colitis had decreased odds of serious adverse events compared to men. Understanding sex-based differences in outcomes allows clinicians to make patient-centered decisions regarding surgical planning and perioperative management for inflammatory bowel disease patients..

show abstract

Common Complications of Surgery for Crohn's Disease and Ulcerative Colitis

Cited by 4 publications

References 120 publications

The effects of postbiotics on chemically-induced colitis in mice: A protocol for a systematic literature review and meta-analysis

The effects of postbiotics on chemically-induced colitis in mice: A protocol for a systematic literature review and meta-analysis

Depression and Anxiety Disorders in Surgically Managed Patients With Inflammatory Bowel Disease

Sex-Based Differences in Inflammatory Bowel Disease Surgical Outcomes

Contact Info

Product

Resources

About