Common Contact Sensitizers among Patients with Hand Eczema: A Multicenter-Study in Nepal

Bhattarai, Shristi; Rijal, Arpana; Agrawal, Sudha

doi:10.3126/njdvl.v14i1.15809

Cited by 2 publications

(3 citation statements)

References 13 publications

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“…57.1%) as majority were housewives (20%) and they were more exposed to household activities, farming, wet works than the males. This female predominance was justified in one of the multicentre studies by Bhattarai S et al [7] done in Nepal in patients with hand eczema. This small scale study gives an overview of contact allergens in different forms of contact dermatitis in our set up.…”

Section: Discussionmentioning

confidence: 98%

Pattern of patch test reactivity among patients with clinical diagnosis of contact dermatitis: A hospital-based study

Parajuli¹,

Paudel²,

Paudel³

et al. 2017

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Introduction:The patterns of positive patch test in Nepal have not been defined so far. The aim of this study was to describe the patterns of patch test reactivity in suspected Allergic Contact Dermatitis (ACD) patients. Methods: This was a hospital based retrospective study performed to investigate patch test reactivity in patients with ACD from April, 2016 through October, 2016. The data of patients who underwent patch test during this period were extracted and analyzed. Results: A total of 35 patients were included in the study. Nineteen (54.3%) tested positive to either one or more allergens. Among them, 17 (89.4%) reacted positively to a single allergen. The following patterns of positives were seen: nickel sulfate, 5 (26.3%), fragrance mix 3 (15.7%), and parthenium 3 (15.7%). Cobalt sulfate, formaldehyde, potassium dichromate, benzocaine, nitrofurazone, chlorocresol each was positive in single patient. Majority of the patients were housewives (22.6%) followed by students and officers (13% each), farmers (10%), health care workers (9.7%), wet work (6.5%) and others (20). Less than half (45%) of the hand eczema showed positive patch test. Similarly,40% of the patient of scattered generalized dermatitis showed reactivity to parthenium, nickel sulfate and multiple antigens. Conclusions: The most common allergens identified were nickel sulfate, fragrance mix and parthenium. Since, there is no well defined contact allergen in the Nepalese community, so patch test kits developed elsewhere might not have been beneficial and calls for need of large scale investigation to identify the local allergens.

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Section: Discussionmentioning

confidence: 98%

Pattern of patch test reactivity among patients with clinical diagnosis of contact dermatitis: A hospital-based study

Parajuli¹,

Paudel²,

Paudel³

et al. 2017

Our Dermatol Online

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“…Nickel sulphate was the most common allergen in various studies including the two studies from Nepal (Table 6). 7,9,12,16,18,19 Nickel sulphate (51.4%) and fragrance mix (37.8%) were the most common allergens in our study. Nickel sulphate followed by fragrance mix were also the most common allergens seen in the systematic review and meta-analysis study of Alinaghi et al 2 Both Hussain et al 17 and Freireich-Astman et al 19 also showed nickel sulphate to be the most common allergen.…”

Section: Discussionmentioning

confidence: 56%

“…In this study the most common allergens among females were nickel sulphate (65.2%) and fragrance mix (26.1%), while, in male fragrance mix (57.1%) was the most common allergen followed by nickel sulphate (28.6%). A study done by Bhattarai et al 18 among patients with hand eczema, also showed nickel sulphate to be the commonest allergen among females.…”

Section: Discussionmentioning

confidence: 90%

Study of Common Allergens in Patients with Allergic Contact Dermatitis: A Hospital Based Study

et al. 2021

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Allergic contact dermatitis (ACD) is one of the most common diseases presenting to the Dermatology department. The one and only method of preventing as well as treating this disease is avoidance of the allergen causing it. The identification of the allergen causing the ACD is possible by performing patch testing. The purpose of this study was to identify common allergens among patients with ACD using Indian standard series (ISS) of patch test. Clinically suspected cases of ACD were included in the hospital based cross-sectional study from January to December 2017. These cases underwent patch testing with the ISS. The study assessed the following variables: sex, age, occupation, site and positive patch test results. There were a total of 58 patients among which, 36.2% were males and 63.8% were females with a mean age of 32.36±12.51 years. Positive patch test reactions were seen in 63.0% of patients. The most common allergens were nickel sulphate (51.4%), fragrance mix (37.8%), potassium dichromate (8.1%), colophony (8.1%) and black rubber mix (8.1%). Among male, most common allergens were fragrance mix (57.1%), nickel sulphate (28.6%) and potassium dichromate (21.4%) while in female, most common allergens were nickel sulphate (65.2%) and fragrance mix (26.1%). In our study, majority of the allergens were positive. Hence, the ISS used in the study might be suitable in the context of Nepalese population. However, further similar studies on large number of patients with multiple allergens are required to determine the exact number of contact allergens prevalent in our population.

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Common Contact Sensitizers among Patients with Hand Eczema: A Multicenter-Study in Nepal

Cited by 2 publications

References 13 publications

Pattern of patch test reactivity among patients with clinical diagnosis of contact dermatitis: A hospital-based study

Pattern of patch test reactivity among patients with clinical diagnosis of contact dermatitis: A hospital-based study

Study of Common Allergens in Patients with Allergic Contact Dermatitis: A Hospital Based Study

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