Common coronary artery occlusions in patients with myocardial infarction

Ahmed, Itedal Abdelraheem Mohamed; Khalid, Nagla Hussein Mohamed; Abd‐Elmagid, Ahmed Elsir Mokhtar; Abdullah, Mawahib Ahmed Mohammed; Musa, Amna Mohammed Idris; AL-Qarni, Nisreen Oudah

doi:10.11604/pamj.2022.42.254.34762

Cited by 7 publications

(3 citation statements)

References 25 publications

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“…13,16 The most common location of infarction in the study was inferior with 20 people (29.9%) followed by inferoposterior infarction locations (25.4%). [17][18][19] The hsTnI levels in this study had a median of 6,519 ng/L. In line with the research by Marston et al…”

Section: Resultssupporting

confidence: 91%

Overview Profile of High Sensitive Troponin I (hsTnI) Levels Based on Infarction Location in Acute Myocardial Infarction Patients: A Single Center Observational Study at Dr. M. Djamil General Hospital, Padang, Indonesia

Hafni,

Rismawati Yaswir,

Desywar

2024

Bioscmed

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Background: Acute myocardial infarction (AMI) remains an important health problem globally. A diagnosis of AMI can be made by finding at least two of the three criteria, namely typical angina pain, electrocardiography (ECG) abnormalities, and increased cardiac biomarkers. Variations in troponin levels based on examination time and infarct location were obtained from previous studies. High-sensitive troponin I (hsTnI) is a very specific biomarker in detecting myocardial damage. This study aims to determine the description of hsTnI levels based on the location of the infarction in AMI patients of Dr. M. Djamil General Hospital Padang. The location of the infarction in AMI determines the management and prognosis for the clinician. Methods: This research is a retrospective study with a cross-sectional design at the Laboratory Installation of Dr. M. Djamil General Hospital Padang. The sample was adult patients diagnosed with AMI with complete data that met the inclusion and exclusion criteria, taken from medical records. Results: This study showed that from a total of 140 AMI patients, 67 samples met the inclusion criteria. A total of 67 AMI patients consisted of 59 men (88.06%) and 8 women (11.94%) with an average age of 60.1 + 10.5 years. The highest hsTnI levels were found at the posterior infarction location, 40,000 ng/L (16,639-48,997). The location of the infarction was dominated by the inferior infarction location in 20 people (29.9%). Conclusion: The highest hsTnI levels were found at the posterior infarction location. The location of the infarction is dominated by the inferior infarction location in AMI patients with ST elevation at Dr. M. Djamil General Hospital Padang.

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Section: Resultssupporting

confidence: 91%

Overview Profile of High Sensitive Troponin I (hsTnI) Levels Based on Infarction Location in Acute Myocardial Infarction Patients: A Single Center Observational Study at Dr. M. Djamil General Hospital, Padang, Indonesia

Hafni,

Rismawati Yaswir,

Desywar

2024

Bioscmed

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“…In terms of the distribution of the culprit vessel, previous studies also agreed with our results, where the most commonly affected coronary vessel was the left anterior descending artery, followed by the right coronary artery, and the least affected vessel was the left circumflex artery [27,32,33]. This is an expected finding since the susceptibility of the coronary arteries for occlusion was previously investigated and lately proved that the LAD artery was the most commonly occluded artery among the coronary arteries (42.4%), followed by the right coronary artery (26.8%) then the left circumflex artery (19.1%) [34][35][36]. Furthermore, lesions were reported to be rare in the right atrial branch, left atrial branch, and posterior left ventricular.…”

Section: Discussionmentioning

confidence: 58%

Deferred vs. Performed Percutaneous Coronary Intervention for Coronary Stenosis with Grey-Zone Fractional Flow Reserve Values

Mohamed Abdelsalam Ali,

Hesham Hegazy,

Mohamed Ahmed

et al. 2023

Int J Clin Cardiol

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Background: Fractional flow reserve (FFR)-guided percutaneous coronary intervention (PCI) has shown better clinical outcomes than conventional angiography-guided PCI. The optimal FFR cut-off value for revascularization is debated. With FFR ≤ 0.75, revascularization for coronary artery disease (CAD) stenosis is associated with improved clinical outcomes, whereas with FFR ≥ 0.8, medical treatment has been shown to result in favorable long-term outcomes. However, there has been controversy over revascularization decision-making for coronary stenosis with FFR between 0.75 and 0.80, the so-called grey zone.Objectives: The present study aims to compare intermediate-term outcomes of performed versus deferred Percutaneous Coronary Intervention in moderate coronary stenosis with FFR values in the grey zone (0.75-0.80) and the primary outcome will be six months major adverse cardiac event (MACE).Methods: A non-randomized prospective clinical study was conducted over 3 years period between January 2019 and January 2022. The study included stable CAD patients with coronary lesions between 40-70% diameter stenosis who underwent FFR study using intracoronary (IC) adenosine and had FFR values between 0.75-0.80 and were divided into two groups: group 1 who have undergone revascularization and group 2 who have undergone deferred revascularization.Results: This study was conducted on 50 patients with moderate coronary artery stenosis with an FFR value in the grey zone undergoing performed or deferred revascularization. The age of the studied group ranged from 38-67 (mean 53.16 ± 7.83) years. The studied group included 12 females (24%) and 38 males (76%). 72% of the patients have diabetes, 70% hypertension, 94% dyslipidaemia and 52% were smokers. There was no significant difference between patients undergoing performed or deferred PCI as regard the risk factors (p-value 0.697).The most common culprit vessel is the left anterior descending (LAD) (64%) followed by right coronary artery (RCA) (20%) then left circumflex (LCX) (16%). 54% of the patients have undergone performed PCI while 46% have undergone deferred PCI with LAD (33.3% and 26.0%) followed by RCA (8.6% and 11.4%) then LCX (7.4% and 8.6%) respectively. There was no significant difference between patients undergoing performed or deferred PCI in regard to either the value of FFR or Culprit vessel (p-value 0.157, 0.232). 87.7% of the patients were asymptomatic after six months, stable and had no MACE. Six patients were symptomatic with MACE 6 patients had target vessel revascularization (TVR) (2 in group 1 and 4 in group 2) with 3 myocardial infarction (MI) (1 post-procedure in group 1 and 2 spontaneous in group 2) and one patient died after 3 months (group 1).

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“…[17][18][19]20 Several other studies demonstrated the LAD artery and LCX artery is most commonly affected compared to RCA. 22,23 LAD artery is the most important and largest blood vessel that carries almost 50% of the blood of the coronary circulation. Blockage of LAD artery may cause myocardial infarction involving large areas of the anterior, septal and apical portions of the heart muscle and lead to serious impairment of cardiac performance.…”

Section: Resultsmentioning

confidence: 99%

Pattern of coronary artery occlusion in patients undergoing coronary angiography at Birat Medical College Teaching Hospital

Shah,

Bista,

2023

J Patan Acad Health Sci

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Introduction: Coronary artery disease (CAD), is the leading cause of death globally. Among different diagnostic and treatment procedures, coronary angiography is considered the gold standard. Birat Medical College Teaching Hospital (BMCTH) is also providing cardiovascular services to people from eastern Nepal and from the neighboring country India. We aim to analyze the pattern of coronary artery occlusion in patients undergoing coronary angiography. Method: A hospital based observational cross-sectional study was conducted at BMCTH from 10 Sep 2022 to 10 Jan 2023. A total of 220 patients were enrolled by consecutive sampling techniques. Ethical approval was obtained from the Institutional Review Committee of BMCTH. Data was collected on baseline characteristics, risk factors, clinical presentation and degree of coronary artery occlusion. Collected data was entered in Microsoft Excel and analyzed by Statistical Package for Social Sciences version 23. Frequency, mean, percentage were calculated. Result: Nearly half (49.1%) patients had significant, 6(2.7%) had intermittent CAD and 14(6.4%) had non critical CAD. Three patients (1.4%) had left main coronary artery disease. Left anterior descending artery 66(30%) was the most commonly involved. Single vessel disease was present in most patients 49(22.27%). Double vessel disease 15(46.8%) and triple vessel disease was more common 14(51.8%) in above 65 y of age. Conclusion: The coronary angiography revealed presence of significant coronary artery disease and multiple vessel involvement with increasing age.

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Common coronary artery occlusions in patients with myocardial infarction

Cited by 7 publications

References 25 publications

Overview Profile of High Sensitive Troponin I (hsTnI) Levels Based on Infarction Location in Acute Myocardial Infarction Patients: A Single Center Observational Study at Dr. M. Djamil General Hospital, Padang, Indonesia

Overview Profile of High Sensitive Troponin I (hsTnI) Levels Based on Infarction Location in Acute Myocardial Infarction Patients: A Single Center Observational Study at Dr. M. Djamil General Hospital, Padang, Indonesia

Deferred vs. Performed Percutaneous Coronary Intervention for Coronary Stenosis with Grey-Zone Fractional Flow Reserve Values

Pattern of coronary artery occlusion in patients undergoing coronary angiography at Birat Medical College Teaching Hospital

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