In this paper, we state and prove the existence of the common fixed points of four maps satisfying a general contractive condition in a cone metric space, thus extending and generalizing several results in literature including the results of Abbas and Jungck (2008) and Abbas, Rhoades and Nazir (2010). We further apply our result to operators of integral type and generalize the results of Khojasteh, Goodarzi, and Razani (2010).