Common Ophthalmic Problems in Pet Rabbits

Wagner, F; Fehr, Michael

doi:10.1053/j.jepm.2007.06.013

Cited by 22 publications

(12 citation statements)

References 28 publications

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“…The domestic rabbit (Oryctolagus cuniculus) has been commonly used on scientific research (Wagner and Fehr 2007). In the field of experimental ophthalmology they are used in tests of new medication, surgical procedures and compatibility of biomaterials to be used in humans (Oriá et al 2006, Werner et al 2006, Kowalski et al 2012.…”

Section: Introductionmentioning

confidence: 99%

Tear production, intraocular pressure and conjunctival microbiota, cytology and histology of New Zealand rabbits (Oryctolagus cuniculus)

Oriá

Gomes²,

Arraes

et al. 2014

Pesq. Vet. Bras.

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RESUMO.-[Produção lacrimal, pressão intraocular, microbiota, citologia e histologia conjuntival de coelhos Nova Zelândia.] O objetivo deste estudo foi estabelecer valores de referência para testes diagnósticos oftálmicos em coelhos da raça Nova Zelândia (Oryctolagus cuniculus). 22 coelhos, machos, adultos foram utilizados. Foi mensurada a produção lacrimal através do teste lacrimal de Shirmer 1 (TLS1) e da Tira endodôntica de papel absorvente (EA-PPTT) de duas marcas comerciais distintas. The purpose of this study was to establish reference values for selected ophthalmic diagnostic tests in New Zealand rabbits (Oryctolagus cuniculus). A total of 22 adult male rabbits were used. The ophthalmic tests included evaluation of tear production with Schirmer tear test 1(STT1) and Endodontic absorbent paper point tear test (EAPPTT) using two different commercial brand materials. Applanation tonometry, Culture of the conjunctival bacterial flora, , conjunctival cytology and conjunctival histology were also performed. Mean (±SD) for STT1, EAPPTTa, EAPPTTb and IOP was 7.27±2.51mm/min, 12.43±1.69mm/min, 15.24±2.07mm/min, 12.89±2.80mm Hg, respectively. Staphylococcus epidermidis, Staphylococcus sp. and Bacillus sp. were predominant. The cytological evaluation revealed the presence columnar epithelial cells, superficial squamous keratinized cells, lymphocytes, heterophils, red blood cells, mucus and bacteria. The histological analysis revealed a stratified epithelium, characterized by the presence of columnar epithelial cells with a large number of goblet cells. The reported data can be used for therapeutic or experimental purposes.INDEX TERMS: Tear production, intraocular pressure, conjunctival microbiota, New Zealand rabbits, Oryctolagus cuniculus, lagomorphs, ophthalmology, Schirmer tear test, tonometry, endodontic paper point. Tear production, intraocular pressure and conjunctival microbiota, cytology and histology of New Zealand rabbits (Oryctolagus cuniculus) histologia revelou epitélio estratificado caracterizado pela presença de células epiteliais colunares com grande núme-ro de células caliciformes. Os achados deste estudo poderão ser utilizados com fins terapêuticos ou experimentais.

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Section: Introductionmentioning

confidence: 99%

Tear production, intraocular pressure and conjunctival microbiota, cytology and histology of New Zealand rabbits (Oryctolagus cuniculus)

Oriá

Gomes²,

Arraes

et al. 2014

Pesq. Vet. Bras.

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“…Ophthalmic examination of the rabbit has been well described as a laboratory model in experimental research. Among ocular lesions, corneal diseases are frequently encountered with corneal ulcerations being the most serious condition . Corneal ulcers are classified as nonhealing, sterile, infected, or rapidly progressive – melting ulcer.…”

Section: Discussionmentioning

confidence: 99%

“…Corneal ulcers are classified as nonhealing, sterile, infected, or rapidly progressive – melting ulcer. These ulcers may be due to a number of factors such as trauma, exposure keratopathy (following anesthesia, orbital disease, buphthalmos, or facial nerve paralysis), eyelid abnormalities, chronic dacryocystitis, or keratoconjunctivitis sicca . Keratomycoses have been induced experimentally in the rabbit with Candida albicans, Aspergillus fumigatus, and Fusarium solani, as part of safety and efficacy testing of various antifungal agents.…”

Section: Discussionmentioning

confidence: 99%

Keratomycosis in a pet rabbit (Oryctolagus cuniculus) treated with topical 1% terbinafine ointment

Bourguet

Guyonnet

Donzel

et al. 2015

Veterinary Ophthalmology

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This report describes the clinical presentation, diagnosis, and medical management of a 2-year-old spayed female dwarf rabbit (Oryctolagus cuniculus) suffering from an ulcerative keratitis and a stromal abscess with a rapid evolution. The diagnosis of fungal keratitis was based on fungal culture identifying the pathogen as Aspergillus fumigatus. Treatment by topical terbinafine was efficacious in resolving the keratomycosis within 8 weeks. To our knowledge, this is the first reported case of spontaneous keratomycosis in a rabbit and the first description of successful therapy by terbinafine.

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“…In rats, retinal dystrophy is a common problem. 19,20 Oculoscopy could be used also as a method for video-ophthalmography 21 for the measuring and recording of eye movements. This could be helpful, especially in case of nystagmus associated with vestibular disease or with other neurologic disorders.…”

Section: Discussionmentioning

confidence: 99%