Common variable immunodeficiency with granulomatous‐lymphocytic interstitial lung disease treated with monoclonal antibodies against <scp>COVID</scp>‐19: A case report

Lechner, Christian; Zöggeler, Thomas; Bellmann, Romuald; Brunner, Jürgen; Zlamy, Manuela; Schirmer, Michael

doi:10.1002/ccr3.6776

Cited by 2 publications

(1 citation statement)

References 15 publications

(26 reference statements)

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“…As a first step of recognizing the value of such a consecutive cohort, single patients with a rare condition, disease, or disease course may be considered for possible publication as a case report. Indeed, from this rheumatic out-patient cohort, cases with significant reduction of pain medication after diagnosis of SpA [22] and the need for accessibility in common variable immunodeficiency with granulomatous-lymphocytic interstitial lung disease (GLILD), who was rapidly and successfully treated with monoclonal antibodies against coronavirus disease 2019 (COVID-19), were already reported [23]. Such case reports may be underrecognized in the literature, but case reports may stimulate the authors to recognize important aspects of their work and the readers to draw attention to specific conditions, diseases, or disease courses.…”

Section: Patient-centered Analyses To Drive Medicine Forwardmentioning

confidence: 97%

Opportunities of digital health technologies for rheumatology: from clinics to quality and research

Schirmer,

Kampik,

Pallua

2024

Explor Musculoskeletal Dis

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Recent developments in digital health technologies are overwhelming, and their use in routine work is still difficult to anticipate. This narrative review summarizes the concept of consecutive cohorts in the literature, together with local research experiences in consecutive rheumatic outpatients. Digital health techniques have to reflect the clinicians’ needs, support real-life care of patients, and allow for the specific assessment of quality parameters fulfilling the Donabedian aspect of qualified health care, using quality indicators to improve health care and research. Rapidly growing observational cohorts will perform best to provide follow-up data as the basis for further development of healthcare approaches for rheumatic patients. The challenges of a selection bias, patients with limited disease expression, and chances of early detection of patients with rare diseases are addressed. For research purposes, sequential analyses with growing cohort size, comparative cross-sectional studies with sequential hypothesis testing and other prognostic, diagnostic, and therapeutic aspects of patient management can be performed. With the support of new technologies, young clinicians can easily approach such clinical topics, and learn about clinical data analyses. The use of quality standards as proposed in international recommendations for diagnostic issues and classification criteria, management recommendations, monitoring, and training issues can be supported by digital technologies. In conclusion, collaborative projects allow detailed clinical analyses of large cohorts, but local initiatives can prepare these co-operations, provide first local logistics and research experiences, and teach clinicians how to perform clinical research. Digital health technologies will strongly support these local initiatives.

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Section: Patient-centered Analyses To Drive Medicine Forwardmentioning

confidence: 97%