Communications: Comparison of Sodium Polyanetholesulfonate with EDTA and Heparin Anticoagulants by Assessing Packed Cell Volume and Blood Smear Quality of Blood from Hybrid White Bass × Striped Bass

Abstract

Sodium polyanetholesulfonate, a synthetic polyanionic detergent compound commonly used as an anticoagulant in human blood culture transfer vials, was compared with EDTA and heparin, in two dilutions, in a pilot study of its anticoagulant abilities with blood from hybrid striped bass (white bass Morone chrysops X striped bass M. saxatilis) . Packed cell volumes (PCVs) and blood smears made from the anticoagulant-treated blood samples were compared across time and with a control . Sodium polyanetholesulfonate kept the hybrid striped bass blood anticoagulated during the 24-h test period, but PCVs and smear quality were significantly different from the other treatments . Sodium polyanetholesulfonate does not appear to perform better than EDTA or heparin as an anticoagulatant for hybrid striped bass blood for hematology analysis .