Sleep disorders are very common among children and young people (CYP) with neurodevelopmental, emotional, behavioural and intellectual disorders (NDEBID). NDEBID include several conditions such as Attention Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder (ASD), Cerebral palsy (CP), Epilepsy and Learning (Intellectual) disorders. Extant literature have reported up to 80% of CYP with NDEBID experiencing different types of chronic insomnia, compared to 3–36% of their otherwise normally developing counterparts. Sleep disorders among CYP with NDEBID have severe negative consequences on the affected individuals and their families. Chronic sleep deprivation causes behavioural, memory and attention problems, mood disorders, impaired cognitive development, learning abilities, and school performances. It also significantly increases the stress level and impact the wellbeing of other family members and impair family cohesion. Sleep disorders therefore further aggravate both internalising and externalising behaviours, emotional wellbeing and daily functioning of CYP with NDEBID. This chapter provides a brief summary of the various important aspects of sleep physiology, aetiology, classification and prevalence of sleep disorders among CYP with NDEBIDs. It outlines various behavioural, non-pharmacological management strategies and pharmacotherapy. Practical tips for clinicians are outlined in an easy-to read flow chart, including sections on assessment, investigations, care plan formulation and follow-up.