Community Septicemia Due to Meticillin-resistant Staphylococcus Aureus, Carriers of Panton-valentine Toxin in Children in Tropical Environments.

Abstract

Community-acquired infections with methicillin-resistant Staphylococcus aureus (MRSA), which produces Panton-Valentine Leukocidin (PVL) or staphylococcal toxic shock toxin (TSST), is rare in children without immune deficiency. Thus pose a threat. In a retrospective study of twelve cases collected from August 1, 2020 to August 31, 2021 in the Pediatrics and Medical Specialties Department of the University Hospital of Angré, we studied the epidemiological, clinical, therapeutic and evolutionary aspects of this often-fatal infection. The average age was 43 months 10 days, with 6/12 girls (50%) and 6/12 boys (50%). The skin lesion was present in 91.7% of patients. Methicillin-resistant Staphylococcus aureus (MRSA) carrying Panton-Valentine's toxin (PVL) was isolated from all children in the blood. Three deaths from septic shock were observed. Anti-staphylococcal antibiotic therapy was administered in all cases. Chest exsufflation was necessary 3 times. The evolution was favorable for 9/12 patients (75%); 8/9 are cured without sequelae (88.9%) and 1/9 a pachypleuritis (11.1%). 3/12 deaths (25%) were recorded.