Generalized multipliers for a left-invertible operator T, whose formal Laurent series $$U_x(z)=\sum _{n=1}^\infty (P_ET^{n}x)\frac{1}{z^n}+\sum _{n=0}^\infty (P_E{T^{\prime *n}}x)z^n$$
U
x
(
z
)
=
∑
n
=
1
∞
(
P
E
T
n
x
)
1
z
n
+
∑
n
=
0
∞
(
P
E
T
′
∗
n
x
)
z
n
, $$x\in \mathcal {H}$$
x
∈
H
actually represent analytic functions on an annulus or a disc are investigated. We show that they are coefficients of analytic functions and characterize the commutant of some left-invertible operators, which satisfies certain conditions in its terms. In addition, we prove that the set of multiplication operators associated with a weighted shift on a rootless directed tree lies in the closure of polynomials in z and $$\frac{1}{z}$$
1
z
of the weighted shift in the topologies of strong and weak operator convergence.