Comorbid non-alcohol substance misuse among people with schizophrenia

Abstract

The high proportion of subjects reporting non-alcohol substance misuse is comparable with figures from the USA. The reports of lifetime misuse most commonly referred to cannabis, psychostimulants, LSD, opiates and anticholinergics. Misuse was concentrated in those younger than 36 years and was reported more often by males.

Quality of life among dually diagnosed and non-substance-using male schizophrenia outpatients

“…This was not consistent with studies reporting that dual [17][18][19][20][21] Schizophrenia patients with no SUD comorbidity showed significantly higher levels of employment, which is consistent with most of the studies in the literature. [20][21][22] Substance use is thought to impair occupational activities and function.…”

Schizophrenia and Addiction

“…In general, SUD is associated with more positive symptoms, aggressive behavior, increased rates of suicide, and poorer sociorehabilitative outcomes in patients with schizophrenia (Duke et al 2001). Moreover, weaker compliance, poorer therapy response, higher relapse frequency, and higher sensitivity to extrapyramidal side effects have been reported in schizophrenic patients with concurrent cannabis use disorder (Lazary 2012).…”

Diretrizes da Federação Mundial das Sociedades de Psiquiatria Biológica para o tratamento biológico da esquizofrenia. Parte 1: tratamento agudo

“…Em estudos mais recentes, a prevalência do abuso ou da dependência de drogas entre pessoas com esquizofrenia em 6 meses e ao longo da vida foi de 27% e 60%, respectivamente (Fowler et al, 1998). O abuso comórbido de drogas não-alcoólicas ao longo da vida foi relatado em 16% da população geral, e o abuso de maconha foi relatado em 60% dos homens esquizofrênicos com menos 36 anos de idade (Duke et al, 2001).…”