Comorbid painful physical symptoms and depression: Prevalence, work loss, and help seeking

Demyttenaere, Koen; Bonnewyn, Anke; Bruffærts, Ronny; Brugha, Terry; Graaf, Ron de; Alonso, Jordi

doi:10.1016/j.jad.2006.01.007

Cited by 182 publications

(150 citation statements)

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“…In our study sample, more than one third of all patients reported a moderate or greater severity of physical pain during the last 4 weeks, which is almost twice the prevalence reported in the general population in Europe (Breivik et al, 2006). As anticipated, and similar to other studies, more severe physical pain was associated with a lower level of education, worse economic situation, and more frequent unemployment (Castillo et al, 2006;Demyttenaere et al, 2006;Tsang et al, 2008). All these variables reflect significantly worse social functioning in alcohol-dependent patients experiencing physical pain in comparison to other individuals with alcohol dependence but mild or no pain.…”

Section: Discussionsupporting

confidence: 88%

“…The prevalence of the experience of physical pain in the general population varies depending on the population and pain conditions examined. The 12-month prevalence of chronic pain conditions in Europe is estimated to be between 17% and 29% (Breivik et al, 2006;Demyttenaere et al, 2006). Problematic alcohol use and/ or alcohol use disorders are also common in European countries, with rates of drinking heavily reaching 25% of the 15-to 64-year-old population and between 3% and 4% of the European general population meeting criteria for alcohol dependence (Popova et al, 2007;Rehm et al, 2015;Wittchen et al, 2011).…”

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confidence: 99%

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Physical Pain in Alcohol-Dependent Patients Entering Treatment in Poland—Prevalence and Correlates

Jakubczyk

Ilgen

Bohnert

et al. 2015

J. Stud. Alcohol Drugs

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ABSTRACT. Objective: Chronic pain and problematic alcohol use commonly co-exist, as the use of alcohol is commonly considered a useful pain self-management strategy. The purpose of this study was to characterize pain and pain-related problems in a group of primary alcohol-dependent individuals entering treatment facilities. Method: A sample of 366 (73.5% men and 26.5% women) alcohol-dependent (according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, criteria) subjects was recruited in alcohol treatment centers in Warsaw, Poland. Information was obtained about demographics, social functioning, sexual and physical abuse during childhood, and severity of alcohol and sleep problems as well as level of impulsivity and general psychopathology. The study group was divided into a "mild or no pain" group and a "moderate or greater pain" group. Results: Among the study group, 34.4% of individuals reported moderate or greater physical pain during the last 4 weeks. The statistical analysis revealed that the experience of physical pain was significantly associated with lower level of education, unemployment, experience of sexual abuse before 18 years of age, and severity of alcohol dependence as well as other potential predictors of relapse (impulsivity, sleep problems, general psychopathology). When entered into logistic regression analysis with other dependent variables, the level of general psychopathology, severity of sleep problems, age, and education were all significantly associated with pain severity. Conclusions: Physical pain is a prevalent and potentially impairing experience in adults seeking treatment for alcohol dependence.

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Section: Discussionsupporting

confidence: 88%

mentioning

confidence: 99%

Physical Pain in Alcohol-Dependent Patients Entering Treatment in Poland—Prevalence and Correlates

Jakubczyk

Ilgen

Bohnert

et al. 2015

J. Stud. Alcohol Drugs

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“…It has been shown that musculoskeletal pain and depression often co-occur (33,34) and that those with both musculoskeletal pain and depressive symptoms have a high probability of work absenteeism (35). In our sample, pain and depressive symptoms also often coexisted, particularly in the trajectory of high SA, with 71% of subjects experiencing both.…”

Section: Haukka Et Almentioning

confidence: 62%

Predictors of sickness absence related to musculoskeletal pain: a two-year follow-up study of workers in municipal kitchens

Haukka¹,

Kaila-Kangas²,

Luukkonen³

et al. 2014

Scand J Work Environ Health

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Predictors of sickness absence related to musculoskeletal pain: a two-year follow-up study of workers in municipal kitchens by Haukka E, Kaila-Kangas L, Luukkonen R, Takala E-P, Viikari-Juntura E, Leino-Arjas P We identified three distinct trajectories of sickness absence (SA) due to musculoskeletal pain among female kitchen workers during two years. Depressive symptoms, musculoskeletal diseases, and multisite pain predicted belonging to a trajectory of high and increasing SA, while multisite pain, smoking, and overweight or obesity predicted belonging to a trajectory of intermediate occurrence of SA. Original article Scand J Work Environ Health. 2014;40(3):278-286. doi:10.5271/sjweh.3415 Predictors of sickness absence related to musculoskeletal pain: a two-year follow-up study of workers in municipal kitchens Haukka E, Kaila-Kangas L, Luukkonen R, Takala E-P, Viikari-Juntura E, Leino-Arjas P. Predictors of sickness absence related to musculoskeletal pain: a two-year follow-up study of workers in municipal kitchens. Scand J Work Environ Health. 2014;40(3):278-286. doi:10.5271/sjweh.3415 AffiliationObjective We studied predictors of sickness absences (SA) due to musculoskeletal pain over two years among 386 municipal female kitchen workers.Methods Pain and SA periods (no/yes) due to pain in seven sites during the past three months were assessed at 3-month intervals over two years by questionnaire. Age, musculoskeletal pain, multisite pain (pain in ≥3 sites), musculoskeletal and other somatic diseases, depressive symptoms, physical and psychosocial workload, body mass index, smoking, and leisure-time physical activity (LTPA) at baseline were considered as predictors. Trajectory analysis and multinomial logistic regression were used.Results Three trajectories of SA emerged, labelled as "none" (41% of the subjects), "intermediate" (48%), and "high" (11%). With the "none" trajectory (no SA) as reference, pain in all musculoskeletal sites excepting the low back predicted belonging to the "intermediate" [odds ratio (OR) 1.82-2.48] or "high" (OR 2.56-3.74) trajectory adjusted for age; multisite pain predicted membership of the "intermediate" [OR 2.15, 95% confidence interval (95% CI) 1.38-3.34] or "high" (OR 4.66, 95% CI 2.10-10.3) trajectories. In a mutually adjusted final model, smoking (OR 2.12, 95% CI 1.22-3.69), multisite pain (OR 1.87, 95% CI 1.15-3.02), and overweight/obesity (OR 1.71, 95% CI 1.08-2.72) predicted belonging to the "intermediate" trajectory, while depressive symptoms (OR 3.57, 95% CI 1.57-8.10), musculoskeletal diseases (OR 3.18, 95% CI 1.37-7.37), and multisite pain (OR 2.72, 95% CI 1.15-6.40) were associated with the "high" trajectory. ConclusionAlong with the number of pain sites and musculoskeletal diseases, attention to depressive symptoms, smoking, and overweight/obesity is needed to tackle SA related to musculoskeletal pain.

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“…Importantly, several medical illnesses such as diabetes, heart disease, autoimmune disorders and pain are common comorbid diagnoses. 4,5 The relation between major depressive disorder and these chronic and disabling conditions appears to be bidirectional because one may influence the prognosis of the other.…”

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confidence: 99%

Neurobiological mechanisms in major depressive disorder

Rot¹,

Mathew²,

Charney³

2009

Canadian Medical Association Journal

378

200

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N early 1 in 5 people will experience a major depressive episode at some point in their lives.1 In this review, we discuss data describing how genes, psychosocial adversity in childhood, and ongoing or recent psychosocial stress may impact multiple neurobiological systems relevant to major depressive disorder. Major depressive disorder may be caused by the cumulative effects of these 3 factors on the brain.

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Comorbid painful physical symptoms and depression: Prevalence, work loss, and help seeking

Cited by 182 publications

References 27 publications

Physical Pain in Alcohol-Dependent Patients Entering Treatment in Poland—Prevalence and Correlates

Physical Pain in Alcohol-Dependent Patients Entering Treatment in Poland—Prevalence and Correlates

Predictors of sickness absence related to musculoskeletal pain: a two-year follow-up study of workers in municipal kitchens

Neurobiological mechanisms in major depressive disorder

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