Comorbidities of Chronic Complete Right Bundle Branch Block and Correlations With Coronary Angiographic Findings

Arham, Ahmad; Bhardwaj, Ravindra; Jain, Abnash C.; Dar, Imran; Jain, Sumesh; Warden, Bradford; Gharib, Wissam; Gharib, Walid

doi:10.1016/j.amjms.2015.10.005

Cited by 4 publications

(2 citation statements)

References 14 publications

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Section: Discussionunclassified

“…Right bundle branch block has been linked to various comorbidities, including pulmonary hypertension, chronic obstructive pulmonary disease, hypertension, and diabetes. [21][22][23] In our population of patients with indications for pacemaker placement, RBBB may signify a more compromised overall clinical condition rather than a cardiac disease signal. Patients with baseline RBBB tended to be older, more frequently male, with chronic kidney disease, but less frequently had a history of atrial fibrillation compared with patients without conduction blocks.…”

Section: Right Bundle Branch Block and Prognosismentioning

confidence: 99%

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Clinical significance and prognostic value of right bundle branch block in permanent pacemaker patients

Mazza,

Bendini,

Leggio

et al. 2024

Journal of Cardiovascular Medicine

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Aims In patients undergoing pacemaker implantation with no prior history of heart failure (HF), the presence of left bundle branch block (LBBB) has been identified as an independent predictor of HF-related death or hospitalization, while the prognostic significance of right bundle branch block (RBBB) remains uncertain. We aimed to assess the long-term risk of all-cause mortality in patients with a standard indication for permanent pacing and normal or moderately depressed left ventricular function when RBBB is detected at the time of implantation. Methods We retrospectively enrolled 1348 consecutive patients who had undergone single- or dual-chamber pacemaker implantation at the study center, from January 1990 to December 2022. Patients with a left ventricular ejection fraction ≤35% or a prior diagnosis of HF were excluded. Results The baseline 12-lead electrocardiogram revealed an RBBB in 241 (18%) and an LBBB in 98 (7%) patients. During a median follow-up of 65 [25th–75th percentile: 32–117] months, 704 (52%) patients died. The combined endpoint of cardiovascular death or HF hospitalization was reached by 173 (13%) patients. On multivariate analysis, RBBB was confirmed as an independent predictor of death [hazard ratio, 1.33; 95% confidence interval (CI), 1.09–1.63; P = 0.005]. However, when considering the combined endpoint of cardiovascular death and HF hospitalization, this endpoint was independently associated with LBBB (hazard ratio, 2.13; 95% CI, 1.38–3.29; P < 0.001), but not with RBBB. Conclusion In patients with standard pacemaker indications and normal or moderately depressed left ventricular function, the presence of basal RBBB was an independent predictor of mortality. However, it was not associated with the combined endpoint of cardiovascular death and HF hospitalization.

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Section: Discussionunclassified

Section: Right Bundle Branch Block and Prognosismentioning

confidence: 99%