Comorbidity of Mental Disorders and Chronic Pain: Chronology of Onset in Adolescents of a National Representative Cohort

Tegethoff, Marion; Belardi, Angelo; Stalujanis, Esther; Meinlschmidt, Gunther

doi:10.1016/j.jpain.2015.06.009

Cited by 145 publications

(104 citation statements)

References 99 publications

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“…Therefore, we could not determine the directionality of the chronic pain-psychopathology relationship in this study. Recent epidemiological research has shown that onset of mental health disorders most often preceded onset of chronic pain in adolescence [30]; however, additional prospective research is needed to establish the temporal relationship between chronic pain and psychopathology.…”

Section: Discussionmentioning

confidence: 99%

“…Recent research with adolescents found associations between chronic pain and affective as well as disruptive behavior disorders [30]. Additionally, in an epidemiological study spanning part of the childhood and adolescent period, Egger and colleagues [8] found gender differences in the relationships between pain and psychopathology.…”

Section: Discussionmentioning

confidence: 99%

“…Indeed, there is a clear link between anxiety, depressive, and disruptive behavior symptoms and disorders and pediatric chronic pain [7; 17; 29; 30]. However, less is known about the relationship of chronic pain in adolescence and lifetime internalizing mental health disorders reported in adulthood.…”

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confidence: 99%

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Chronic pain in adolescence and internalizing mental health disorders

Noel

Groenewald

Beals-Erickson

et al. 2016

Pain

169

130

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Chronic pain in childhood and adolescence has been shown to heighten risk for depressive and anxiety disorders in specific samples in adulthood; however, less is known about the association between a wider variety of chronic pains and internalizing mental health disorders. Using nationally representative data, the objectives of this study were to establish prevalence rates of internalizing mental health disorders (anxiety and depressive disorders) among cohorts with or without adolescent chronic pain, and to examine whether chronic pain in adolescence is associated with lifetime history of internalizing mental health disorders reported in adulthood. Data from the National Longitudinal Study of Adolescent to Adult Health (Add Health) was used (N = 14,790). Individuals who had chronic pain in adolescence subsequently reported higher rates of lifetime anxiety disorders (21.1% vs. 12.4%) and depressive disorders (24.5% vs. 14.1%) in adulthood as compared to individuals without a history of adolescent chronic pain. Multivariate logistic regression confirmed that chronic pain in adolescence was associated with an increased likelihood of lifetime history of anxiety (odds ratio (OR): 1.33; 95% confidence interval (CI): 1.09-1.63, p=0.005) and depressive disorders (OR: 1.38; CI: 1.16-1.64, p<0.001) reported in adulthood. Future research is needed to examine neurobiological and psychological mechanisms underlying these co-morbidities.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Chronic pain in adolescence and internalizing mental health disorders

Noel

Groenewald

Beals-Erickson

et al. 2016

Pain

169

130

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“…21 In addition, poor sleep quality and anxiety have been established as possible comorbidities of chronic pain. 22,23 Research has demonstrated that chronic pain is associated with sensitization of the central nucleus of the amygdala and is involved in pain-related anxiety. GABAergic inhibition has been observed in chronic pain conditions as well.…”

Section: Discussionmentioning

confidence: 99%

Multimodal Care in the Management of a Patient With Chronic Tendinopathy of the Biceps Femoris: A Case Report

Martin

2017

Journal of Chiropractic Medicine

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Objective: The purpose of this case report was to describe the use of dry needling in conjunction with auricular acupuncture, core exercises, and light aerobic activity for treating chronic tendinopathy of the biceps femoris. Clinical Features: A 30-year-old white female presented with chronic biceps femoris tendinopathy. The injury had occurred 18 months prior while training for a triathlon. Active stretching of her right biceps femoris while standing with her feet 6 inches apart aggravated the pain at the origin in the right tendon of the biceps femoris at 0 degrees of movement. Intervention/Outcome: The combination of dry needling and auricular acupuncture with core rehabilitation exercises and light activity was employed. Alleviation of pain with full range of motion was achieved during hip extension, knee flexion, and standing biceps femoris stretch at the 11th, 16th, and 18th treatments. In addition, the patient also reported improvement in her symptoms, including night sweats, insomnia, anxiety, tension, and constipation. Conclusions: This patient's symptoms and function improved after 18 treatments of multimodal care. Dry needling employed simultaneously with auricular acupuncture, core exercises, and light activity could be considered a possible strategy for treating chronic tendinopathy. (J Chiropr Med 2017;16:156-162)

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“…What research has shown us is that it is actually not one single thing that causes the chronic pain and dysfunction, but that it really is a large number of individual pieces of straw which breaks the camel's back. We have found that children who have underling anxiety or depression are more likely to develop chronic pain [5]. A big issue we find is what we call catastrophizing, a personality trait especially among parents and kids which is rumination and magnifying the problem and constantly being obsessed about the symptoms [6].…”

Section: Interview Friedrichsdorf Future Science Groupmentioning

confidence: 94%

Multimodal Pediatric Pain Management (Part 2)

Friedrichsdorf

2017

Pain Manag.

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Dr Stefan Friedrichsdorf speaks to Commissioning Editor Jade Parker: Stefan Friedrichsdorf, MD, is medical director of the Department of Pain Medicine, Palliative Care and Integrative Medicine at Children's Hospitals and Clinics of Minnesota in Minneapolis/St Paul, MN, USA, home to one of the largest and most comprehensive programs of its kind in the country. The pain and palliative care program is devoted to control acute, chronic/complex and procedural pain for inpatients and outpatients in close collaboration with all pediatric subspecialties at Children's Minnesota. The team also provides holistic, interdisciplinary care for children and teens with life limiting or terminal diseases and their families. Integrative medicine provides and teaches integrative, nonpharmacological therapies (such as massage, acupuncture/acupressure, biofeedback, aromatherapy and self-hypnosis) to provide care that promotes optimal health and supports the highest level of functioning in all individual children's activities. In this second part of the interview they discuss multimodal (opioid-sparing) analgesia for hospitalized children in pain and how analgesics and adjuvant medications, interventions, rehabilitation, psychological and integrative therapies act synergistically for more effective pediatric pain control with fewer side effects than a single analgesic or modality.

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Comorbidity of Mental Disorders and Chronic Pain: Chronology of Onset in Adolescents of a National Representative Cohort

Cited by 145 publications

References 99 publications

Chronic pain in adolescence and internalizing mental health disorders

Chronic pain in adolescence and internalizing mental health disorders

Multimodal Care in the Management of a Patient With Chronic Tendinopathy of the Biceps Femoris: A Case Report

Multimodal Pediatric Pain Management (Part 2)

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