Comorbidity of Obesity and Pain in a General Population: Results from the Southern Pain Prevalence Study

Hitt, Holli C.; McMillen, Robert; Thornton-Neaves, Tonya; Koch, Karen; Cosby, Arthur G.

doi:10.1016/j.jpain.2006.12.003

Cited by 235 publications

(200 citation statements)

References 13 publications

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“…The mechanism behind this association remains unclear, but in both the general population and in patients with RA, pain prevalence and severity have been linked to obesity (33), and pain in RA has a large impact on self-reported health and physical function.…”

Section: Discussionmentioning

confidence: 99%

Association of obesity with worse disease severity in rheumatoid arthritis as well as with comorbidities: A long‐term followup from disease onset

Ajeganova

Andersson

Hafström

2012

Arthritis Care & Research

198

158

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Objective. To determine the association of obesity, defined as a body mass index (BMI) >30 or >28 kg/m 2 or by waist circumference (WC), with disease activity and severity, as well as its relationship to comorbidities in rheumatoid arthritis (RA). 9% at baseline and 15.8% at followup. In multivariable regression, BMI and obesity, defined as a BMI >30 or >28 kg/m 2 , at both inclusion and the time of the survey were independently associated with higher disease activity, fewer patients in sustained remission, higher HAQ score, more pain, and worse general health. Also, BMI and obesity independently conferred to higher odds for being diagnosed with hypertension, diabetes mellitus, and chronic pulmonary disease. Further, BMI and WC were independently associated with angina pectoris/acute myocardial infarction/coronary revascularization. In contrast, none of the examined obesity variables was associated with the prevalence of stroke or transient ischemic attack. Lifestyle changes during the observational period, such as quitting smoking or diet change, had no impact on the outcomes. Conclusion. Obesity was associated with worse RA disease outcomes and a higher prevalence of comorbidities. Body measurements are recommended to improve prediction of the disease course.

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Section: Discussionmentioning

confidence: 99%

Association of obesity with worse disease severity in rheumatoid arthritis as well as with comorbidities: A long‐term followup from disease onset

Ajeganova

Andersson

Hafström

2012

Arthritis Care & Research

198

158

View full text Add to dashboard Cite

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“…1 Estimate trends in body mass index (BMI) in women have shown that age standardized prevalence of obesity increased from 6.4% in 1975 to 14.9% in 2014. 2 Obesity is considered a very serious public health issue because it is associated with multiple co-morbidities 3 including damage to organs as diverse as the heart, brain, liver, lungs, vessels, as well as to joints 4 and bone skeleton. 5 …”

Section: Introductionmentioning

confidence: 99%

Vitamin D alteration associated with obesity and bariatric surgery

Lespessailles

Toumi

2017

Exp Biol Med (Maywood)

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Obesity and severe obesity constitute growing serious health problems reaching epidemic proportion in most countries with a prevalence increasing from 6.4 in 1975 to 14.9% in 2014. This present review summarizes currently available data on vitamin D deficiencies in the obese population before and after bariatric surgery. The important evidence emerging from our evaluation confirms that obese patients are at risk of multiple nutritional deficiencies, especially vitamin D deficiency, before bariatric surgery. Our survey confirms that the precise role of the gut microbiome and its associated changes on the vitamin D metabolism after the different bariatric surgery procedures has not yet been studied. Furthermore, whether differences in the microbiota may alter the therapeutic responses to vitamin D is not known. AbstractObesity and severe obesity constitute growing serious health problems reaching epidemic proportion in most countries. Interactions and relationships between obesity and bone tissue and its metabolism are complex but are more and more studied and recognized. Obesity is associated with an altered hormonal profile including particularly bone-regulating hormones like vitamin D. Bariatric surgery procedures, thanks to their effectiveness to achieve therapeutic endpoints for comorbidities associated with obesity, have had an increasing success. However, these surgeries by producing mechanical restriction and or malabsorption syndrome lead to nutritional deficiencies including vitamin D. In this review, we aim to (1) discuss the nutritional deficiency of vitamin D in the obese, (2) to summarize the different surgical options in bariatric surgery and to present the evidence concerning these procedures and their associated profile in vitamin D post-operative insufficiency, (3) to present the different recommendations in clinical practice to prevent or treat vitamin D deficiencies or insufficiencies in patients treated by bariatric surgery and finally to introduce emerging assumptions on the relationship between vitamin D, microbiota composition and circulating bile acids.

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“…According to Hitt et al (24) , obese patients have greater probability of suffering from back pain as compared to those who are not obese, with 1470-fold greater chances for grade I, 1993 for grade II, and 1505 for grade III.…”

Section: Discussionmentioning

confidence: 99%

“…The authors also observed that patients without lower limb arthralgia walked more before surgery when compared to those who presented with pain, with no significant differences after the operation (26) . Pain symptoms are the most eminent characteristic of hip osteoarthritis (24) . It is worth mentioning that this study did not have the objective of diagnosing osteoarthritis.…”

Section: Discussionmentioning

confidence: 99%

“…Hitt et al (24) utilized multiple regression analysis to determine the relation between the BMI and the origin and category of body pain, demonstrating that the increase of one point in the BMI can elevate by 0.16 the reference of body pain in the sites reported. In this study it was possible to observe the relation between low back pain and weight, which was strongly influenced by the mental health aspect.…”

Section: Discussionmentioning

confidence: 99%

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Quality of life and prevalence of osteoarticular pain in patients submitted to bariatric surgery

Grans

Warth

Farah

et al. 2012

Einstein (São Paulo)

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Objective: To analyze quality of life and observe the prevalence of musculoskeletal pain in patients submitted to bariatric surgery. Methods: A prospective, observational and comparative study with 26 individuals aged 18 to 60 years, 25 women, which included two evaluations, one preoperative and the other approximately 42 months after surgery. The Medical Outcomes Study 36-Item Short Form Health Survey (SF-36) and the Human Body Diagram with Visual Analogue Scale were employed. Results: The individual samples showed grade III obesity, with a predominance of postoperative overweight, hypertension and diabetes in 65.4% and 42.3% of the samples, with remission of hypertension in 50% and of diabetes mellitus in 38.5% (p<0.001). The SF-36 demonstrated improved quality of life, especially in aspects related to motricity; vitality and mental health showed no significant changes. Osteoarticular pain was reported and identified in various sites by the subjects; however, 87.5% of patients in the preoperative period and 88.5% in the postoperative period reported not having any physical therapy orientation, while 65.4% reported being engaged in some type of regular physical activity after surgery (p<0.001). Conclusion: Morbidly obese individuals have a high probability of suffering from clinical, psychic, and musculoskeletal alterations, compromising their quality of life and showing improvement after bariatric surgery; on the other hand, the psycho-emotional manifestations did not progress in the same way.Keywords: Pain, postoperative/etiology; Arthralgia/etiology; Obesity; Bariatric surgery; Quality of life RESUMO Objetivo: Analisar a qualidade de vida e observar a prevalência de dor musculoesquelética em pacientes submetidos à cirurgia bariátrica.Métodos: Estudo prospectivo, observacional e comparativo, incluindo 26 amostras, idade entre 18 e 60 anos, sendo 25 mulheres e compreendendo duas avaliações, uma pré-operatória e outra cerca de 42 meses após a cirurgia, com aplicação do Medical Outcomes Study 36-Item Short Form Health Survey (SF-36) e do Diagrama do Corpo Humano com Escala Visual Analógica. Resultado: As amostras apresentaram obesidade grau III, com predomínio de sobrepeso após cirurgia, hipertensão e diabetes presentes em 65,4% e 42,3% das amostras, com remissão da hipertensão em 50% e da diabete mellitus em 38,5% (p<0,001). O SF-36 evidenciou melhora da qualidade de vida, sobretudo nos aspectos relacionados à motricidade; vitalidade e saúde mental não apresentaram mudanças significativas. A dor osteoarticular esteve presente e foi apontada em diversos pontos pelos sujeitos da amostra; contudo, 87,5% dos pacientes no pré e 88,5% no pós-operatório relataram não ter realizado nenhum acompanhamento fisioterápico, enquanto 65,4% relataram fazer algum tipo de atividade física regularmente após a cirurgia (p<0,001). Conclusão: Obesos mórbidos apresentam alta probabilidade de sofrer com as alterações clínicas, psíquicas e musculoesqueléticas, comprometendo sua qualidade de vida e apresentando melhora após a ci...

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Comorbidity of Obesity and Pain in a General Population: Results from the Southern Pain Prevalence Study

Cited by 235 publications

References 13 publications

Association of obesity with worse disease severity in rheumatoid arthritis as well as with comorbidities: A long‐term followup from disease onset

Association of obesity with worse disease severity in rheumatoid arthritis as well as with comorbidities: A long‐term followup from disease onset

Vitamin D alteration associated with obesity and bariatric surgery

Quality of life and prevalence of osteoarticular pain in patients submitted to bariatric surgery

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