2014
DOI: 10.1186/1471-2261-14-73
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Comorbidity profiles and inpatient outcomes during hospitalization for heart failure: an analysis of the U.S. Nationwide inpatient sample

Abstract: BackgroundTreatment of heart failure (HF) is particularly complex in the presence of comorbidities. We sought to identify and associate comorbidity profiles with inpatient outcomes during HF hospitalizations.MethodsLatent mixture modeling was used to identify common profiles of comorbidities during adult hospitalizations for HF from the 2009 Nationwide Inpatient Sample (n = 192,327).ResultsMost discharges were characterized by "common" comorbidities. A "lifestyle" profile was characterized by a high prevalence… Show more

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Cited by 57 publications
(55 citation statements)
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“…Increased comorbid burden was associated with increased odds for other infections, postoperative pneumonia, and at least 1 of 15 different complications. This finding is consistent with prior studies examining complications across a wide array of surgical procedures (Dimick et al, 2003;Allareddy et al;Lee et al, 2014). Patients with high comorbid burden are likely to be medically compromised, which makes them more prone to infection-related complications, as found in the current study.…”
Section: Discussionsupporting
confidence: 93%
“…Increased comorbid burden was associated with increased odds for other infections, postoperative pneumonia, and at least 1 of 15 different complications. This finding is consistent with prior studies examining complications across a wide array of surgical procedures (Dimick et al, 2003;Allareddy et al;Lee et al, 2014). Patients with high comorbid burden are likely to be medically compromised, which makes them more prone to infection-related complications, as found in the current study.…”
Section: Discussionsupporting
confidence: 93%
“…renal failure) [89] diagnosis of AHF even more difficult in frail older patients. Some comorbidities such as anemia, renal failure and hyperglycaemia, may influence the short and long-term prognoses [9093]. The treatment of concurrent conditions in the frail older patients with AHF should be optimized by balancing the risk–benefit relation (prioritizations, interactions or contraindications) and making adjustments according to creatinine clearance (MDRD-4).…”
Section: Frailty-based Management In Older Patients With Ahfmentioning
confidence: 99%
“…The finding from our study of hospitalized sepsis patients shows similar predictors of IMV, and also helps stratify the risk based on different age groups. A higher Charlson comorbidity index, a widely used index for measuring disease burden, which has been validated by NIS database analyses as a reliable measure of disease burden [15,16], positively correlated with an increased odds of invasive ventilation.…”
Section: Discussionmentioning
confidence: 99%