Antenna design considerations for implantable devices in remote telehealth systems Take-Home Messages • Implantable sensors are pivotal to telehealth systems enabling continuous monitoring of a patient's vital health signs wirelessly. • Antennas are an integral element of these systems whose design is a complex task due to harsh and highly volatile in-body environment and requirements of robust and reliable performance while offering miniature structure, patient safety and biocompatibility. • A comprehensive critical review on the antenna design for implantable medical devices highlighting requirements, challenges, antenna types and human body effects on their performance shows that slotted patch antennas operating at higher frequencies can serve the purpose optimally. • The slotted patch antenna designed in the light of recommendations made offers a small size of 7.5×5×0.25 mm 3 with a-10 dB bandwidth of 25 MHz, a near-omnidirectional pattern and a gain of 1.7 dBi. • The paper can serve as a reference for the antenna designers working in the field of implantable devices providing state-of-the-art, current advancements, requirements, challenges as well as design rules.