A miniaturized half-mode substrate-integrated-waveguide (HMSIW) based bandpass filter with defected ground surface (DGS) for sub-5G applications is presented in this research. The novelty in this article is the proposal of an original configuration of a SIW Filter composed of a mix of DGS cells; each couple of C shapes is etched exactly beneath of two cross shapes, which give us long rejection. We have used six periodic cross-shaped slots as DGS in top of the cavity plane for disturbing the current and creating stopband rejection, and we have also used three couples of C-shaped DGS cells in the bottom plane to improve the performances of the proposed filter. This novel bandpass filter is developed on a 1.54 mm-thick FR-4 (with relative permittivity of 4.3 and tangent loss of 0.025) operating in the band ranging from 3.4 GHz to 3.8 GHz with a bandwidth of 400 MHz and having the size of 13.5 × 38.6 mm 2 . The proposed HMSIW-based filter is simulated, fabricated, and measured. The measurement results are in decent agreement with the simulation results.