Comparação da perviedade entre artéria radial e veia safena em pacientes em pós-operatório de cirurgia de revascularização miocárdica com retorno dos sintomas

Hortmann, Herbert Coelho; Oliveira, Homero Geraldo de; Rabello, Renato Rocha; Rocha, Eduardo; Oliveira, Sérgio Caporali de

doi:10.1590/s0102-76382010000200014

Cited by 8 publications

(8 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Contrasting former studies, which evaluate the RA and SV graft patency in symptomatic patients by angiography ( 1 , 2 , 11 - 15 ), this investigation compared the mid-term follow up of the RA and SV patency rate in asymptomatic patients using a noninvasive diagnostic modality-CT coronary angiography. This work discovered that in the asymptomatic patients, the RA conduits had a suitable patency in two to five years.…”

Section: Discussionmentioning

confidence: 99%

“…For example, Tranbaugh et al ( 3 ) demonstrated favorable long-term (14 years) survival using the LITA, SV, and an RA conduit for CABG by comparison to using the LITA and SV. In contrast, Hortmann et al ( 2 ) showed that the RA presented worse results than did the SV as a second graft in CABG, particularly in women who were grafted in the right coronary artery. Also, Fukui et al ( 11 ) reported that the one year patency rate of the RA was significantly lower than that of the free right ITA and SV graft.…”

Section: Introductionmentioning

confidence: 95%

“…The patency of the arterial grafts has been shown to be better comparing with venous grafts ( 1 ). The use of the left internal thoracic artery (LITA) grafted to the left anterior descending branch (LAD) of the left coronary artery has been established as the gold standard in CABG courtesy of its high patency in the mid- and long-term in comparison with the saphenous vein SV ( 2 ). Nonetheless, consensus has yet to emerge amongst experts as to what constitutes the second best conduit for CABG ( 3 ).…”

Section: Introductionmentioning

confidence: 99%

“…The use of the SV as an aortocoronary conduit shows an acceptable short-term patency rate, which is similar to that of the use of the radial artery (RA) ( 4 - 6 ); however, its medium-term patency rate is liable to deteriorate, significantly ( 4 ). Several clinical reports support the use of RA conduits in preference to SV conduits ( 1 , 4 , 7 - 10 ), while there are other studies that suggest the opposite ( 2 , 4 , 11 ). For example, Tranbaugh et al ( 3 ) demonstrated favorable long-term (14 years) survival using the LITA, SV, and an RA conduit for CABG by comparison to using the LITA and SV.…”

Section: Introductionmentioning

confidence: 99%

“…Most studies conducted till now on graft patency rates recruited symptomatic patients ( 2 , 12 ), drawing upon such different diagnostic modalities as coronary angiography ( 1 , 12 , 15 ) and CT angiography ( 16 ).…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Mid-Term Patency in Radial Artery and Saphenous Vein After Coronary Artery Bypass Grafting in Asymptomatic Patients Using 128-Slice CT Coronary Angiography

et al. 2015

View full text Add to dashboard Cite

Background:Patency of the revascularization conduit is an essential predictor of long-standing survival after coronary artery bypass grafting.Objectives:We have conducted this study to compare the mid-term patency rates of radial artery (RA), left internal thoracic artery (LITA) and also saphenous vein (SV) grafts in asymptomatic patients following coronary artery bypass graft surgery (CABG) undergoing total IV anesthesia.Patients and Methods:In this study, 30 three-vessel disease patients with 104 RA, LITA, and SV grafts used concomitantly for primary isolated non-emergent CABG surgery were assessed. The primary end point was CT angiographic graft patency rate. After 53.5 (24-97) months’ follow-up, graft patency was assessed using 128-slice CT coronary angiography. Logistic regression analysis was used to detect the independent predictors of graft failure.Results:A total of 104 grafts, including 30 LITA, 44 SV, and 30 RA grafts, were studied. Cumulative graft patency rates were 93.3% in LITA, 83.3% in RA, and 70.5% in SV grafts. Statistically significant difference was found between the LITA and the SV graft patency rates (P = 0.019), whereas the difference between the RA conduit patency and the LITA or SV graft patency rates did not have any statistical significance (P = 0.424 and P = 0.273, respectively). Independent predictors of RA grafts occlusion were native coronary stenosis < 70% and female gender.Conclusions:In our patients, the RA grafts had an acceptable patency rate in 2 to 5 years’ follow-up. Although the SV grafts had a relatively higher patency rate than RA grafts in our asymptomatic patients, the patency rates in RA and SV grafts were close to each other. The RA graft function was poor in the patients with a higher number of risk factors and in the females.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 95%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Mid-Term Patency in Radial Artery and Saphenous Vein After Coronary Artery Bypass Grafting in Asymptomatic Patients Using 128-Slice CT Coronary Angiography

et al. 2015

View full text Add to dashboard Cite

show abstract

Pathophysiology of Lesions in Coronary Bypass

Gabriel¹,

Oliveira²

2016

Coronary Graft Failure

View full text Add to dashboard Cite

Angiotensin II, as well as 5-hydroxytriptamine, is a potent vasospasm inducer of saphenous vein graft for coronary artery bypass grafting in patients with diabetes mellitus

Yokota

Gamoh

Tanaka-Totoribe

et al. 2016

Biochemistry and Biophysics Reports

View full text Add to dashboard Cite

Diabetes mellitus (DM) is an important risk factor for adverse outcomes of coronary artery bypass grafting. The bypass grafts harvested from patients with DM tend to go into spasm after their implantation into the coronary circulation. To clarify the contribution of 5-hydroxytriptamine (5-HT) and angiotensin II (AngII) in the bypass graft spasm, we examined the contractile reactivity to 5-HT or AngII of isolated human endothelium-denuded saphenous vein (SV) harvested from DM and non-DM patients. The 5-HT-induced constriction of the SV was significantly augmented in the DM group than in the non-DM group, which is similar to our previous report. AngII-induced constriction of the SV was also significantly augmented in the DM group than the non-DM group. Especially in the non-DM group, the AngII-induced maximal vasoconstriction was markedly lower than the 5-HT-induced one. Meanwhile, the increasing rates of AngII-induced vasoconstriction in the DM group to the non-DM group were significantly greater than those of 5-HT-induced vasoconstriction. These results indicate that 5-HT is a potent inducer of SV graft spasm in both DM and non-DM patients, while AngII is a potent inducer of SV graft spasm only in patients with DM. Furthermore, the protein level of AngII AT1 receptor (AT1R), but not the protein level of 5-HT2A receptor, in the membrane fraction of the SV smooth muscle cells of DM patients was significantly increased as compared with that of the non-DM patients. These results suggest that the mechanism for hyperreactivity to AngII in the SV from DM patients is due to, at least in part, the increase in the amount of AT1R on membrane of the SV smooth muscle cells.

show abstract

Comparação da perviedade entre artéria radial e veia safena em pacientes em pós-operatório de cirurgia de revascularização miocárdica com retorno dos sintomas

Cited by 8 publications

References 15 publications

Mid-Term Patency in Radial Artery and Saphenous Vein After Coronary Artery Bypass Grafting in Asymptomatic Patients Using 128-Slice CT Coronary Angiography

Mid-Term Patency in Radial Artery and Saphenous Vein After Coronary Artery Bypass Grafting in Asymptomatic Patients Using 128-Slice CT Coronary Angiography

Pathophysiology of Lesions in Coronary Bypass

Angiotensin II, as well as 5-hydroxytriptamine, is a potent vasospasm inducer of saphenous vein graft for coronary artery bypass grafting in patients with diabetes mellitus

Contact Info

Product

Resources

About